ArticleGenome research2011
Emergence of male-biased genes on the chicken Z-chromosome: sex-chromosome contrasts between male and female heterogametic systems.
Article in Genome research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- RASA1 expression highlights Z/W dosage dynamics and gonadal development in chickens.BMC genomics · 2025Article
- ZW and XY Sex Chromosomes Drive Rapid and Distinctive Evolution of Sex-Biased Gene Expression.Molecular ecology · 2025Article
- A sex-linked supergene with large effects on sperm traits has little impact on reproductive traits in female zebra finches.Proceedings. Biological sciences · 2024Article
- Sex chromosome evolution among amniotes: is the origin of sex chromosomes non-random?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Sex-biased gene expression and recent sex chromosome turnover.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Transcriptomic and Epigenetic Preservation of Genetic Sex Identity in Estrogen-feminized Male Chicken Embryonic Gonads.Endocrinology · 2021Article
- The Female-Specific W Chromosomes of Birds Have Conserved Gene Contents but Are Not Feminized.Genes · 2020Article
- Recessive Z-linked lethals and the retention of haplotype diversity in a captive butterfly population.Heredity · 2020Article
- Article
- RNA sequencing reveals a complete but an unconventional type of dosage compensation in the domestic silkwormRoyal Society open science · 2017Article
- Quantitative Mass Spectrometry Reveals Partial Translational Regulation for Dosage Compensation in Chicken.Molecular biology and evolution · 2015Article
- Transcriptome assemblies for studying sex-biased gene expression in the guppy, Poecilia reticulata.BMC genomics · 2014Article
- Lack of dosage compensation accompanies the arrested stage of sex chromosome evolution in ostriches.Molecular biology and evolution · 2013Article
- Masculinization of the x chromosome in the pea aphid.PLoS genetics · 2013Article
- Transcriptome sequencing reveals the character of incomplete dosage compensation across multiple tissues in flycatchers.Genome biology and evolution · 2013Article
- Trade-off between selection for dosage compensation and masculinization on the avian Z chromosome.Genetics · 2012Article
- Segmental dataset and whole body expression data do not support the hypothesis that non-random movement is an intrinsic property of Drosophila retrogenes.BMC evolutionary biology · 2012Article
- Expression reduction in mammalian X chromosome evolution refutes Ohno's hypothesis of dosage compensation.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Disentangling the relationship between sex-biased gene expression and X-linkage.Genome research · 2012Article
- Retrogenes moved out of the z chromosome in the silkworm.Journal of molecular evolution · 2012Article
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1 author.
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Abstract
There has been extensive traffic of male-biased genes out of the mammalian and Drosophila X-chromosomes, and there are also reports of an under-representation of male-biased genes on the X. This may reflect an adaptive process driven by natural selection where an autosomal location of male-biased genes is favored since male genes are only exposed to selection one-third of the time when X-linked. However, there are several alternative explanations to "out-of-the-X" gene movement, including mutational bias and a means for X-linked genes to escape meiotic sex chromosome inactivation (MSCI) during spermatogenesis. As a critical test of the hypothesis that genomic relocation of sex-biased genes is an adaptive process, I examined the emergence, and loss, of genes on the chicken Z-chromosome, i.e., a female heterogametic system (males ZZ, females ZW). Here, the analogous prediction would be an emergence of male-biased genes onto, not a loss from, the Z-chromosome because Z is found more often in males than autosomes are. I found that genes expressed in testis but not in ovary are highly over-represented among genes that have emerged on the Z-chromosome during avian evolution. Moreover, genes with male-biased expression are similarly over-represented among new Z-chromosomal genes. Interestingly, genes with female-biased expression have more often moved from than to the Z-chromosome. These observations show that male and female heterogametic organisms display opposing directionalities in the emergence and loss of sex-biased genes on sex chromosomes. This is consistent with theoretical models on the evolution of sexually antagonistic genes in which new mutations are at least partly dominant.
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