Evidence map›Paper›PMID 21868595›Full record

ArticleClinical pediatrics2012

Economic and radiation costs of initial imaging approaches after a child's first febrile urinary tract infection.

Jonathan C Routh, Frederick D Grant, Paul J Kokorowski, Caleb P Nelson, Frederic H Fahey, S Ted Treves, Richard S Lee

Open access · greenAbstract readComparative Study
In one paragraph

Article in Clinical pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  6. Review
  7. Relevance of current guidelines in the management of VUR.European journal of pediatrics · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jonathan C RouthChildren's Hospital Boston, Harvard Medical School, Boston, MA, USA.
Frederick D Grant
Paul J Kokorowski
Caleb P Nelson
Frederic H Fahey
S Ted Treves
Richard S Lee
Boston Children's Hospital · USHarvard University · US

Funding

Training in Child Health Services Research and Implementation ScienceT32HS000063 · AHRQ · CHILDREN'S HOSPITAL BOSTON · PI GARABEDIAN, LAURA FADEN, WALSH, KATHLEEN ELIZABETH · 1994 to 2024
$7.6M
Research Training in Pediatric Urology/CHB T32T32DK060442 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI ADAM, ROSALYN M · 2002 to 2023
$2.5M
Clinical Outcomes for Siblings of Children with Vesico-Ureteral RefluxK23DK088943 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI NELSON, CALEB PENNELL · 2010 to 2014
$892k
Comparative Effectiveness of Vesicoureteral Reflux Treatments in ChildrenK08DK100534 · NIDDK · DUKE UNIVERSITY · PI ROUTH, JONATHAN C · 2014 to 2018
$671k
AHRQ HHS T32 HS000063AHRQ HHS T32-HS000063NIDDK NIH HHS 32-DK60442NIDDK NIH HHS K08 DK100534NIDDK NIH HHS K23 DK088943NIDDK NIH HHS K23-DK088943NIDDK NIH HHS T32 DK060442
6 · The paper itself

Abstract

BACKGROUND. The traditional initial imaging approach following pediatric urinary tract infection is the "bottom-up" approach (cystogram and renal ultrasound). Recently, the "top-down" approach (nuclear renal scan followed by cystogram for abnormal scans only) has gained increasing attention. The relative cost and radiation doses of these are unknown METHODS. The authors used a decision model to evaluate these imaging approaches. Cost and effective radiation dose estimates, including sensitivity analyses, were based on one-time imaging only. RESULTS. Comparing hypothetical cohorts of 100 000 children, the top-down imaging approach cost $82.9 million versus $59.2 million for the bottom-up approach. Per-capita effective radiation dose was 0.72 mSv for top-down compared with 0.06 mSv for bottom-up. CONCLUSIONS. Routine use of nuclear renal scans in children following initial urinary tract infection diagnosis would result in increased imaging costs and radiation doses as compared to initial cystogram and ultrasound. Further data are required to clarify the long-term clinical implications of this increase.

Indexed as

AlgorithmsCost-Benefit AnalysisDecision Support TechniquesFemaleFeverHumansInfantMaleRadiation DosageRadionuclide ImagingRadiopharmaceuticalsSensitivity and SpecificityTechnetium Tc 99m Dimercaptosuccinic AcidUltrasonographyUrinary Tract InfectionsVesico-Ureteral RefluxRadiopharmaceuticalsTechnetium Tc 99m Dimercaptosuccinic Acid

Identifiers

PMID21868595
PMCPMC3792796
OpenAlexW2118873997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.