Evidence map›Paper›PMID 21867956›Full record

ArticleThe Lancet. Infectious diseases2011

Antiscience and ethical concerns associated with advocacy of Lyme disease.

Paul G Auwaerter, Johan S Bakken, Raymond J Dattwyler, J Stephen Dumler, John J Halperin, Edward McSweegan, Robert B Nadelman, Susan O'Connell, Eugene D Shapiro, Sunil K Sood and 3 more

Abstract read
In one paragraph

Article in The Lancet. Infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 122 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Persistent Symptoms After Treatment of Lyme Disease.Infectious disease clinics of North America · 2022
    Review
  6. Why are people antiscience, and what can we do about it?Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Lyme Disease Frontiers: ReconcilingPathogens (Basel, Switzerland) · 2019
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 2 countries.

Paul G AuwaerterDivision of Infectious Diseases, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA. pgauwaerter@gmail.com
Johan S Bakken
Raymond J Dattwyler
J Stephen Dumler
John J Halperin
Edward McSweegan
Robert B Nadelman
Susan O'Connell
Eugene D Shapiro
Sunil K Sood
Allen C Steere
Arthur Weinstein
Gary P Wormser
New York Medical College · USJohns Hopkins University · USCohen Children's Medical Center · USIcahn School of Medicine at Mount Sinai · USMassachusetts General Hospital · USSouthampton General Hospital · GBSt. Luke's Hospital · USWashington Hospital · USYale University · US

Funding

YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Yale University Clinical and Translational Science Award ProgramKL2RR024138 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$4.8M
The Effectiveness of Vaccines in Clinical PracticeK24RR022477 · NCRR · YALE UNIVERSITY · PI SHAPIRO, EUGENE DAVID · 2006 to 2010
$760k
NCATS NIH HHS UL1 TR000142NCRR NIH HHS K24 RR022477NCRR NIH HHS KL2 RR024138NCRR NIH HHS UL1 RR024139
6 · The paper itself

Abstract

Advocacy for Lyme disease has become an increasingly important part of an antiscience movement that denies both the viral cause of AIDS and the benefits of vaccines and that supports unproven (sometimes dangerous) alternative medical treatments. Some activists portray Lyme disease, a geographically limited tick-borne infection, as a disease that is insidious, ubiquitous, difficult to diagnose, and almost incurable; they also propose that the disease causes mainly non-specific symptoms that can be treated only with long-term antibiotics and other unorthodox and unvalidated treatments. Similar to other antiscience groups, these advocates have created a pseudoscientific and alternative selection of practitioners, research, and publications and have coordinated public protests, accused opponents of both corruption and conspiracy, and spurred legislative efforts to subvert evidence-based medicine and peer-reviewed science. The relations and actions of some activists, medical practitioners, and commercial bodies involved in Lyme disease advocacy pose a threat to public health.

Indexed as

Borrelia burgdorferiAnti-Bacterial AgentsChronic DiseaseConsumer AdvocacyHumansLyme DiseasePhysiciansPractice Guidelines as TopicProfessional MisconductPropagandaAnti-Bacterial Agents

Identifiers

PMID21867956
PMCPMC4489928
OpenAlexW2141592193

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.