ArticleNeuron2011
A synaptic strategy for consolidation of convergent visuotopic maps.
Article in Neuron, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Connectivity, Computation, and Plasticity of the Early Visual System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Wiring subcortical image-forming centers: Topography, laminar targeting, and map alignment.Current topics in developmental biology · 2021Review
- Distinct Developmental Mechanisms Act Independently to Shape Biased Synaptic Divergence from an Inhibitory Neuron.Current biology : CB · 2020Article
- SAP102 regulates synaptic AMPAR function through a CNIH-2-dependent mechanism.Journal of neurophysiology · 2018Article
- Visual subcircuit-specific dysfunction and input-specific mispatterning in the superior colliculus of fragile X mice.Journal of neurodevelopmental disorders · 2018Article
- Visual Maps Development: Reconsidering the Role of Retinal Efnas and Basic Principle of Map Alignment.Frontiers in cellular neuroscience · 2018Article
- Article
- Novel Models of Visual Topographic Map Alignment in the Superior Colliculus.PLoS computational biology · 2016Article
- Theory of Connectivity: Nature and Nurture of Cell Assemblies and Cognitive Computation.Frontiers in neural circuits · 2016Article
- Interplay of cell-autonomous and nonautonomous mechanisms tailors synaptic connectivity of converging axons in vivo.Neuron · 2014Article
- Differential requirement for NMDAR activity in SAP97β-mediated regulation of the number and strength of glutamatergic AMPAR-containing synapses.Journal of neurophysiology · 2014Article
- Homocysteine reduces NMDAR desensitization and differentially modulates peak amplitude of NMDAR currents, depending on GluN2 subunit composition.Journal of neurophysiology · 2013Article
- Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Eye opening and PSD95 are required for long-term potentiation in developing superior colliculus.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Synapse maturation is enhanced in the binocular region of the retinocollicular map prior to eye opening.Journal of neurophysiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
The mechanisms by which experience guides refinement of converging afferent pathways are poorly understood. We describe a vision-driven refinement of corticocollicular inputs that determines the consolidation of retinal and visual cortical (VC) synapses on individual neurons in the superficial superior colliculus (sSC). Highly refined corticocollicular terminals form 1-2 days after eye-opening (EO), accompanied by VC-dependent filopodia sprouting on proximal dendrites, and PSD-95 and VC-dependent quadrupling of functional synapses. Delayed EO eliminates synapses, corticocollicular terminals, and spines on VC-recipient dendrites. Awake recordings after EO show that VC and retina cooperate to activate sSC neurons, and VC light responses precede sSC responses within intervals promoting potentiation. Eyelid closure is associated with more protracted cortical visual responses, causing the majority of VC spikes to follow those of the colliculus. These data implicate spike-timing plasticity as a mechanism for cortical input survival, and support a cooperative strategy for retinal and cortical coinnervation of the sSC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.