Evidence map›Paper›PMID 21867759›Full record

ArticleNeuroImage2012

3D fiber tractography with susceptibility tensor imaging.

Chunlei Liu, Wei Li, Bing Wu, Yi Jiang, G Allan Johnson

Abstract read
In one paragraph

Article in NeuroImage, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Article
  2. Histological Properties of a Chemically Fixed Human Embryo Visualized with Quantitative Susceptibility Mapping.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  3. Article
  4. Article
  5. Asymmetric susceptibility tensor imaging.Magnetic resonance in medicine · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. MRI tools for assessment of microstructure and nephron function of the kidney.American journal of physiology. Renal physiology · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chunlei LiuBrain Imaging and Analysis Center, School of Medicine, Duke University, 2424 Erwin Rod, Suite 501, Durham, NC 27705, USA. chunlei.liu@duke.edu
Wei Li
Bing Wu
Yi Jiang
G Allan Johnson

Funding

X-RAY RESEARCH AND DEVELOPMENT WITH/WITHOUT LIVE ANIMALSP41RR005959 · NCRR · DUKE UNIVERSITY · PI PANDIT, PRACHI · 1990 to 2011
$16.0M
Small Animal Imaging Resource ProgramU24CA092656 · NCI · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2007 to 2011
$2.2M
High Resolution Diffusion-Weighted Magnetic Resonance Imaging at 300-Micron LevelR00EB007182 · NIBIB · DUKE UNIVERSITY · PI LIU, CHUNLEI · 2009 to 2011
$999k
NCI NIH HHS U24 CA092656NCRR NIH HHS P41 RR005959NIBIB NIH HHS R00 EB007182NIBIB NIH HHS R00EB007182
6 · The paper itself

Abstract

Gradient-echo MRI has revealed anisotropic magnetic susceptibility in the brain white matter. This magnetic susceptibility anisotropy can be measured and characterized with susceptibility tensor imaging (STI). In this study, a method of fiber tractography based on STI is proposed and demonstrated in the mouse brain. STI experiments of perfusion-fixed mouse brains were conducted at 7.0T. The magnetic susceptibility tensor was calculated for each voxel with regularization and decomposed into its eigensystem. The major eigenvector is found to be aligned with the underlying fiber orientation. Following the orientation of the major eigenvector, we are able to map distinctive fiber pathways in 3D. As a comparison, diffusion tensor imaging (DTI) and DTI fiber tractography were also conducted on the same specimens. The relationship between STI and DTI fiber tracts was explored with similarities and differences identified. It is anticipated that the proposed method of STI tractography may provide a new way to study white matter fiber architecture. As STI tractography is based on physical principles that are fundamentally different from DTI, it may also be valuable for the ongoing validation of DTI tractography.

Indexed as

AlgorithmsAnimalsBrainDiffusion Tensor ImagingImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalMiceMice, Inbred C57BLNerve Fibers, MyelinatedPattern Recognition, AutomatedReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID21867759
PMCPMC3235503

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.