ArticleBMC plant biology2011
Global transcriptome analysis of two ameiotic1 alleles in maize anthers: defining steps in meiotic entry and progression through prophase I.
Article in BMC plant biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 33 citations in OpenAlex.
- Identification of cDNA-AFLP fragments associated with the B chromosome from different developmental stages of maize anthers.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025Article
- The plant early recombinosome: a high security complex to break DNA during meiosis.Plant reproduction · 2024Review
- Genetic Regulation of Mitosis-Meiosis Fate Decision in Plants: Is Callose an Oversighted Polysaccharide in These Processes?Plants (Basel, Switzerland) · 2023Review
- Isolation of Meiocytes and Cytological Analyses of Male Meiotic Chromosomes in Soybean, Lettuce, and Maize.Methods in molecular biology (Clifton, N.J.) · 2023Article
- A cascade of bHLH-regulated pathways programs maize anther development.The Plant cell · 2022Article
- Dynamic localization of SPO11-1 and conformational changes of meiotic axial elements during recombination initiation of maize meiosis.PLoS genetics · 2020Article
- Discovering and Constructing ceRNA-miRNA-Target Gene Regulatory Networks during Anther Development in Maize.International journal of molecular sciences · 2019Article
- Stage-Specific Gene Profiling of Germinal Cells Helps Delineate the Mitosis/Meiosis Transition.Plant physiology · 2018Article
- Tackling Plant Meiosis: From Model Research to Crop Improvement.Frontiers in plant science · 2018Review
- Rye (Secale cereale) supernumerary (B) chromosomes associated with heat tolerance during early stages of male sporogenesis.Annals of botany · 2017Article
- Long non-coding RNAs are major contributors to transcriptome changes in sunflower meiocytes with different recombination rates.BMC genomics · 2016Article
- Spatiotemporally dynamic, cell-type-dependent premeiotic and meiotic phasiRNAs in maize anthers.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Global Identification of Genes Specific for Rice Meiosis.PloS one · 2015Article
- Transcriptomes and proteomes define gene expression progression in pre-meiotic maize anthers.G3 (Bethesda, Md.) · 2014Article
- The transcriptome landscape of early maize meiosis.BMC plant biology · 2014Article
- Maize germinal cell initials accommodate hypoxia and precociously express meiotic genes.The Plant journal : for cell and molecular biology · 2014Article
- Transcriptomic landscape of prophase I sunflower male meiocytes.Frontiers in plant science · 2014Article
- Recent advances in understanding of meiosis initiation and the apomictic pathway in plants.Frontiers in plant science · 2014Review
- The meiotic transcriptome architecture of plants.Frontiers in plant science · 2014Review
- Cytological characterization and allelism testing of anther developmental mutants identified in a screen of maize male sterile lines.G3 (Bethesda, Md.) · 2013Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDevelopmental cues to start meiosis occur late in plants. Ameiotic1 (Am1) encodes a plant-specific nuclear protein (AM1) required for meiotic entry and progression through early prophase I. Pollen mother cells (PMCs) remain mitotic in most am1 mutants including am1-489, while am1-praI permits meiotic entry but PMCs arrest at the leptotene/zygotene (L/Z) transition, defining the roles of AM1 protein in two distinct steps of meiosis. To gain more insights into the roles of AM1 in the transcriptional pre-meiotic and meiotic programs, we report here an in depth analysis of gene expression alterations in carefully staged anthers at 1 mm (meiotic entry) and 1.5 mm (L/Z) caused by each of these am1 alleles.
results1.0 mm and 1.5 mm anthers of am1-489 and am1-praI were profiled in comparison to fertile siblings on Agilent® 4 × 44 K microarrays. Both am1-489 and am1-praI anthers are cytologically normal at 1.0 mm and show moderate transcriptome alterations. At the 1.5-mm stage both mutants are aberrant cytologically, and show more drastic transcriptome changes. There are substantially more absolute On/Off and twice as many differentially expressed genes (sterile versus fertile) in am1-489 than in am1-praI. At 1.5 mm a total of 4,418 genes are up- or down-regulated in either am1-489 or am1-praI anthers. These are predominantly stage-specific transcripts. Many putative meiosis-related genes were found among them including a small subset of allele-specific, mis-regulated genes specific to the PMCs. Nearly 60% of transcriptome changes in the set of transcripts mis-regulated in both mutants (N = 530) are enriched in PMCs, and only 1% are enriched in the tapetal cell transcriptome. All array data reported herein will be deposited and accessible at MaizeGDB http://www.maizegdb.org/.
conclusionsOur analysis of anther transcriptome modulations by two distinct am1 alleles, am1-489 and am1-praI, redefines the role of AM1 as a modulator of expression of a subset of meiotic genes, important for meiotic progression and provided stage-specific insights into the genetic networks associated with meiotic entry and early prophase I progression.
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