ArticleThe journal of physical chemistry. B2011
Two-photon optical properties of near-infrared dyes at 1.55 μm excitation.
Article in The journal of physical chemistry. B, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- NIR Excitation in Atomically Precise Nanoclusters via Two-Photon and Three-Photon Absorption.Accounts of chemical research · 2026Article
- Near-infrared light activatable chemically induced CRISPR system.Light, science & applications · 2025Article
- Two-Photon Absorption: An Open Door to the NIR-II Biological Window?Frontiers in chemistry · 2022Review
- Shortwave Infrared Imaging with J-Aggregates Stabilized in Hollow Mesoporous Silica Nanoparticles.Journal of the American Chemical Society · 2019Article
- Molecular Engineering and Structure-Related Properties of Squaraine Dyes Based on the Core and Wings Concept.ACS omega · 2018Article
- Deep Tissue Imaging with Multiphoton Fluorescence Microscopy.Current opinion in biomedical engineering · 2017Article
- Article
- Multispectral measurement of contrast in tissue-mimicking phantoms in near-infrared spectral range of 650 to 1600 nm.Journal of biomedical optics · 2014Article
- Multispectral imaging in the extended near-infrared window based on endogenous chromophores.Journal of biomedical optics · 2013Article
- All-near-infrared multiphoton microscopy interrogates intact tissues at deeper imaging depths than conventional single- and two-photon near-infrared excitation microscopes.Journal of biomedical optics · 2013Article
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Authors and funding
7 authors.
Funding
Abstract
Two-photon (2P) optical properties of cyanine dyes were evaluated using a 2P fluorescence spectrophotometer with 1.55 μm excitation. We report the 2P characteristics of common NIR polymethine dyes, including their 2P action cross sections and the 2P excited fluorescence lifetime. One of the dyes, DTTC, showed the highest 2P action cross-section (∼103 ± 19 GM) and relatively high 2P excited fluorescence lifetime and can be used as a scaffold for the synthesis of 2P molecular imaging probes. The 2P action cross-section of DTTC and the lifetime were also highly sensitive to the solvent polarity, providing other additional parameters for its use in optical imaging and the mechanism for probing environmental factors. Overall, this study demonstrated the quantitative measurement of 2P properties of NIR dyes and established the foundation for designing molecular probes for 2P imaging applications in the NIR region.
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