ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Frequency-dependent tuning of the human motor system induced by transcranial oscillatory potentials.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
112 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Is transcranial alternating current stimulation effective for improving working memory? A three-level meta-analysis.Psychonomic bulletin & review · 2025Pooled it
- Effects of transcranial alternating current stimulation on motor performance and motor learning for healthy individuals: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Guideline
- No aftereffects of high current density 10 Hz and 20 Hz tACS on sensorimotor alpha and beta oscillations.Scientific reports · 2021Trial
- A specific phase of transcranial alternating current stimulation at the β frequency boosts repetitive paired-pulse TMS-induced plasticity.Scientific reports · 2021Trial
- State-dependent effects of transcranial oscillatory currents on the motor system: what you think matters.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- Is transcranial alternating current stimulation effective in modulating brain oscillations?PloS one · 2013Trial
- Article
- Transcranial Direct Current Stimulation Enhances Motor Performance by Modulating Beta-Phase Synchronization in the Sensorimotor Network: A Preliminary Study.Brain sciences · 2025Article
- Neural mechanisms underlying the after-effects of repetitive paired-pulse TMS with Β tACS on the human primary motor cortex.Scientific reports · 2025Article
- μ-Transcranial Alternating Current Stimulation Induces Phasic Entrainment and Plastic Facilitation of Corticospinal Excitability.The European journal of neuroscience · 2025Article
- Bifocal tACS over the primary sensorimotor cortices increases interhemispheric inhibition and improves bimanual dexterity.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Neuroplastic effects of transcranial alternating current stimulation (tACS): from mechanisms to clinical trials.Frontiers in human neuroscience · 2025Review
- Transcranial alternating current stimulation can modulate the blink reflex excitability. Effects of a 10- and 20-Hz tACS session on the blink reflex recovery cycle in healthy subjects.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- 20 Hz temporal interference stimulation can more effectively enhance motor evoked potentials in the primary motor cortex.Frontiers in human neuroscience · 2025Article
- The Modulatory Effects of Transcranial Alternating Current Stimulation on Brain Oscillatory Patterns in the Beta Band in Healthy Older Adults.Brain sciences · 2024Article
- The role of the somatosensory system in the feeling of emotions: a neurostimulation study.Social cognitive and affective neuroscience · 2024Article
- An overview of the effects and mechanisms of transcranial stimulation frequency on motor learning.Journal of neuroengineering and rehabilitation · 2024Review
- Does 20 Hz Transcranial Alternating Current Stimulation over the Human Primary Motor Cortex Modulate Beta Rebound Following Voluntary Movement?Brain sciences · 2024Article
- Beta tACS of varying intensities differentially affect resting-state and movement-related M1-M1 connectivity.Frontiers in neuroscience · 2024Article
52 more citing papers are in PubMed but not listed here.
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Different corticothalamic brain modules intrinsically oscillate at a "natural frequency" in a topographically organized manner. In "quiescent" human sensorimotor regions, the main detectable oscillatory activity peaks at ∼20 Hz, and partly contributes to determine the state of corticospinal excitability. Here, we showed that the transcranial application of an imperceptible, short-lasting (90 s) electric field oscillating at a physiological range increases corticospinal excitability online, with well defined frequency dependence and regional specificity. Indeed, the size of motor evoked potentials (MEPs) induced by navigated single-pulse TMS over the motor cortex significantly increased only during the local application of transcranial alternating current stimulation (tACS) at 20 Hz (β range). Other tACS frequencies (5, 10, and 40 Hz) applied on the motor cortex did not impact MEPs' size. Moreover, tACS applied on a control site (parietal cortex) and on a peripheral site (ulnar nerve) also failed to modulate MEPs. These results help clarifying the functional significance of the 20 Hz idling β rhythm of sensorimotor regions and suggest potential clinical applications of this approach.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.