Evidence map›Paper›PMID 21864897›Full record

ArticleBiomaterials2011

Subtleties of biomineralisation revealed by manipulation of the eggshell membrane.

Nan Li, Li-na Niu, Yi-pin Qi, Cynthia K Y Yiu, Heonjune Ryou, Dwayne D Arola, Ji-hua Chen, David H Pashley, Franklin R Tay

Abstract read
In one paragraph

Article in Biomaterials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Avian Egg: A Multifaceted Biomaterial for Tissue Engineering.Industrial & engineering chemistry research · 2021
    Article
  5. Article
  6. Review
  7. Article
  8. Multiphase intrafibrillar mineralization of collagen.Angewandte Chemie (International ed. in English) · 2013
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nan LiCollege of Osteopedics & Traumatology, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Li-na Niu
Yi-pin Qi
Cynthia K Y Yiu
Heonjune Ryou
Dwayne D Arola
Ji-hua Chen
David H Pashley
Franklin R Tay

Funding

Biomimetic remineralization of resin-dentin bondsR21DE019213 · NIDCR · AUGUSTA UNIVERSITY · PI TAY, FRANKLIN CHI MENG · 2009 to 2010
$362k
NIDCR NIH HHS R21 DE019213
6 · The paper itself

Abstract

Biocalcification of collagen matrices with calcium phosphate and biosilicification of diatom frustules with amorphous silica are two discrete processes that have intrigued biologists and materials scientists for decades. Recent advancements in the understanding of the mechanisms involved in these two biomineralisation processes have resulted in the use of biomimetic strategies to replicate these processes separately using polyanionic, polycationic or zwitterionic analogues of extracellular matrix proteins to stabilise amorphous mineral precursor phases. To date, there is a lack of a universal model that enables the subtleties of these two apparently dissimilar biomineralisation processes to be studied together. Here, we utilise the eggshell membrane as a universal model for differential biomimetic calcification and silicification. By manipulating the eggshell membrane to render it permeable to stabilised mineral precursors, it is possible to introduce nanostructured calcium phosphate or silica into eggshell membrane fibre cores or mantles. We provide a model for infiltrating the two compartmental niches of a biopolymer membrane with different intrafibre minerals to obtain materials with potentially improved structure-property relationships.

Indexed as

AnimalsBiomimeticsCalcification, PhysiologicCalcium PhosphatesChickensEgg ShellMembranesMineralsPermeabilitySilicon Dioxidecalcium phosphateCalcium PhosphatesMineralsSilicon Dioxide

Identifiers

PMID21864897
PMCPMC3183170

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.