ArticleAnalytical chemistry2011
Separation of a set of peptide sequence isomers using differential ion mobility spectrometry.
Article in Analytical chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Untargeted Discovery and Localization of Isomerized Residues in Neuropeptides.Analytical chemistry · 2025Article
- Composite Multidimensional Ion Mobility-Mass Spectrometry for Improved Differentiation of Stereochemical Modifications.Analytical chemistry · 2023Article
- Linear and Differential Ion Mobility Separations of Middle-Down Proteoforms.Analytical chemistry · 2018Article
- Variables Affecting the Internal Energy of Peptide Ions During Separation by Differential Ion Mobility Spectrometry.Journal of the American Society for Mass Spectrometry · 2017Article
- Distinguishing d- and l-aspartic and isoaspartic acids in amyloid β peptides with ultrahigh resolution ion mobility spectrometry.Chemical communications (Cambridge, England) · 2017Article
- Localization of Post-Translational Modifications in Peptide Mixtures via High-Resolution Differential Ion Mobility Separations Followed by Electron Transfer Dissociation.Journal of the American Society for Mass Spectrometry · 2016Article
- Rapid and High-Throughput Detection and Quantitation of Radiation Biomarkers in Human and Nonhuman Primates by Differential Mobility Spectrometry-Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2016Article
- To What Extent is FAIMS Beneficial in the Analysis of Proteins?Journal of the American Society for Mass Spectrometry · 2016Article
- Structural Characterization of Anticancer Drug Paclitaxel and Its Metabolites Using Ion Mobility Mass Spectrometry and Tandem Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2016Article
- Improved Differential Ion Mobility Separations Using Linked Scans of Carrier Gas Composition and Compensation Field.Journal of the American Society for Mass Spectrometry · 2015Article
- Separation of opiate isomers using electrospray ionization and paper spray coupled to high-field asymmetric waveform ion mobility spectrometry.Journal of the American Society for Mass Spectrometry · 2015Article
- Description of gas-phase ion/neutral interactions in differential ion mobility spectrometry: CV prediction using calibration runs.Journal of the American Society for Mass Spectrometry · 2014Article
- Optimization of peptide separations by differential ion mobility spectrometry.Journal of the American Society for Mass Spectrometry · 2014Article
- Site-specific characterization of (D)-amino acid containing peptide epimers by ion mobility spectrometry.Analytical chemistry · 2014Article
- Large-scale analysis of peptide sequence variants: the case for high-field asymmetric waveform ion mobility spectrometry.Analytical chemistry · 2013Article
- Protein analysis by shotgun/bottom-up proteomics.Chemical reviews · 2013Review
- Probing the complementarity of FAIMS and strong cation exchange chromatography in shotgun proteomics.Journal of the American Society for Mass Spectrometry · 2013Article
- High-resolution differential ion mobility spectrometry of a protein.Analytical chemistry · 2013Article
- Pushing the Frontier of High-Definition Ion Mobility Spectrometry Using FAIMS.Mass spectrometry (Tokyo, Japan) · 2013Article
- High-field asymmetric waveform ion mobility spectrometry for mass spectrometry-based proteomics.Expert review of proteomics · 2012Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Protein identification in bottom-up proteomics requires disentangling isomers of proteolytic peptides, a major class of which are sequence inversions. Their separation using ion mobility spectrometry (IMS) has been limited to isomeric pairs. Here we demonstrate baseline separation of all seven 8-mer tryptic peptide isomers using differential IMS. Evaluation of peak capacity implies that even larger libraries should be resolved for heavier peptides with higher charge states.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.