Evidence map›Paper›PMID 21863375›Full record

ReviewCellular and molecular life sciences : CMLS2011

Transcriptional control of natural killer cell differentiation and function.

Alfonso Martín-Fontecha, Graham M Lord, Hugh J M Brady

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alfonso Martín-FontechaMedical Research Council (MRC) Centre for Transplantation, Guy's Hospital, King's College London, 5th floor Tower Wing, London SE1 9RT, UK. alfonso.martin-fontecha@kcl.ac.uk
Graham M Lord
Hugh J M Brady
Guy's Hospital · GBImperial College London · GB

Funding

Department of HealthMedical Research Council G0802068Medical Research Council G0901737Medical Research Council G1000758
6 · The paper itself

Abstract

Gene expression can be modulated depending on physiological and developmental requirements. A multitude of regulatory genes, which are organized in interdependent networks, guide development and eventually generate specific phenotypes. Transcription factors (TF) are a key element in the regulatory cascade controlling cell fate and effector functions. In this review, we discuss recent data on the diversity of TF that determine natural killer (NK) cell fate and NK cell function.

Indexed as

Cell DifferentiationTranscription, GeneticCell MovementHumansKiller Cells, NaturalTranscription FactorsTranscription Factors

Identifiers

PMID21863375
PMCPMC11114505
OpenAlexW2017277626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.