Trial reportCerebral cortex (New York, N.Y. : 1991)2012
Word intelligibility and age predict visual cortex activity during word listening.
Trial report in Cerebral cortex (New York, N.Y. : 1991), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Translation of task-evoked negative BOLD response into aging and Alzheimer's disease: a systematic review of the current literature.Journal of translational medicine · 2025Pooled it
- The Temporal Resolution Needed for Speech Intelligibility Assessed with Mosaic Speech: Effects of Block Duration, Age, and Word Familiarity.Audiology research · 2026Article
- Cortical Network Activity Associated With Different Types of Word Recognition Errors by Older Adults.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Effects of Age on the Neural Tracking of Speech in Noise.Brain sciences · 2025Article
- Deep learning-driven dyslexia detection model using multi-modality data.PeerJ. Computer science · 2024Article
- Evidence for cortical adjustments to perceptual decision criteria during word recognition in noise.NeuroImage · 2022Article
- Unique patterns of hearing loss and cognition in older adults' neural responses to cues for speech recognition difficulty.Brain structure & function · 2022Article
- Fully synthetic neuroimaging data for replication and exploration.NeuroImage · 2020Article
- Cingulo-opercular adaptive control for younger and older adults during a challenging gap detection task.Journal of neuroscience research · 2020Article
- What Can Computational Models Learn From Human Selective Attention? A Review From an Audiovisual Unimodal and Crossmodal Perspective.Frontiers in integrative neuroscience · 2020Review
- Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition.Neurobiology of language (Cambridge, Mass.) · 2020Article
- Resting state functional connectivity predictors of treatment response to electroconvulsive therapy in depression.Scientific reports · 2019Article
- Orthographic influence on spoken word identification: Behavioral and fMRI evidence.Neuropsychologia · 2018Article
- Article
- Task-Related Vigilance During Word Recognition in Noise for Older Adults with Hearing Loss.Experimental aging research · 2016Article
- Effects of Aging and Adult-Onset Hearing Loss on Cortical Auditory Regions.Frontiers in neuroscience · 2016Review
- Cingulo-Opercular Function During Word Recognition in Noise for Older Adults with Hearing Loss.Experimental aging research · 2016Article
- Flexibility and Stability in Sensory Processing Revealed Using Visual-to-Auditory Sensory Substitution.Cerebral cortex (New York, N.Y. : 1991) · 2015Article
- Cortical activity predicts which older adults recognize speech in noise and when.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- The cingulo-opercular network provides word-recognition benefit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
The distractibility that older adults experience when listening to speech in challenging conditions has been attributed in part to reduced inhibition of irrelevant information within and across sensory systems. Whereas neuroimaging studies have shown that younger adults readily suppress visual cortex activation when listening to auditory stimuli, it is unclear the extent to which declining inhibition in older adults results in reduced suppression or compensatory engagement of other sensory cortices. The current functional magnetic resonance imaging study examined the effects of age and stimulus intelligibility in a word listening task. Across all participants, auditory cortex was engaged when listening to words. However, increasing age and declining word intelligibility had independent and spatially similar effects: both were associated with increasing engagement of visual cortex. Visual cortex activation was not explained by age-related differences in vascular reactivity but rather auditory and visual cortices were functionally connected across word listening conditions. The nature of this correlation changed with age: younger adults deactivated visual cortex when activating auditory cortex, middle-aged adults showed no relation, and older adults synchronously activated both cortices. These results suggest that age and stimulus integrity are additive modulators of crossmodal suppression and activation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.