Evidence map›Paper›PMID 21862320›Full record

ReviewCurrent opinion in structural biology2011

Visualizing kinetochore architecture.

Gregory Alushin, Eva Nogales

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in structural biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. AI-Assisted Forward Modeling of Biological Structures.Frontiers in cell and developmental biology · 2019
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Towards physiological complexity with in vitro single-molecule biophysics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gregory AlushinBiophysics Graduate Group, UC Berkeley, Berkeley, CA 94720, United States.
Eva Nogales
University of California, Berkeley · US

Funding

TUBULIN STRUCTURE BY ELECTRON CRYSTALLOGRAPHYP01GM051487 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI CATE, JAMIE H · 1994 to 2018
$27.6M
Howard Hughes Medical InstituteNIGMS NIH HHS P01 GM051487
6 · The paper itself

Abstract

Kinetochores are large macromolecular assemblies that link chromosomes to spindle microtubules (MTs) during mitosis. Here we review recent advances in the study of core MT-binding kinetochore complexes using electron microcopy methods in vitro and nanometer-accuracy fluorescence microscopy in vivo. We synthesize these findings in novel three-dimensional models of both the budding yeast and vertebrate kinetochore in different stages of mitosis. There is a growing consensus that kinetochores are highly dynamic, supra-molecular machines that undergo dramatic structural rearrangements in response to MT capture and spindle forces during mitosis.

Indexed as

AnimalsCell Cycle ProteinsCytoskeletal ProteinsFungal ProteinsHumansKinetochoresMetaphaseMicroscopy, ElectronMicroscopy, FluorescenceMicrotubule-Associated ProteinsMicrotubulesModels, MolecularNuclear ProteinsProtein ConformationSaccharomycetalesSpindle ApparatusCell Cycle ProteinsCytoskeletal ProteinsFungal ProteinsMicrotubule-Associated ProteinsNDC80 protein, humanNuclear Proteins

Identifiers

PMID21862320
PMCPMC3189262
OpenAlexW2024795146

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.