Evidence map›Paper›PMID 21861777›Full record

ArticleAIDS research and human retroviruses2012

Measurements of immune responses for establishing correlates of vaccine protection against HIV.

Wendy A Burgers, Amapola Manrique, David Masopust, Lyle R McKinnon, Matthew R Reynolds, Morgane Rolland, Catherine Blish, Gerald K Chege, Rhonda Curran, William Fischer and 2 more

Open access · greenAbstract readConference Proceedings
In one paragraph

Article in AIDS research and human retroviruses, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Improving Adherence to Post-Cervical Biopsy Sexual Abstinence in Kenyan Female Sex Workers.American journal of reproductive immunology (New York, N.Y. : 1989) · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Wendy A BurgersInstitute of Infectious Diseases and Molecular Medicine and Division of Medical Virology, University of Cape Town, Cape Town, South Africa.
Amapola Manrique
David Masopust
Lyle R McKinnon
Matthew R Reynolds
Morgane Rolland
Catherine Blish
Gerald K Chege
Rhonda Curran
William Fischer
Carolina Herrera
D Noah Sather
University of Cape Town · ZACenter for Infectious Disease Research · USImperial College London · GBStanford University · USUniversity of Minnesota Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Well-defined correlates of protective immunity are an essential component of rational vaccine development. Despite years of basic science and three HIV vaccine efficacy trials, correlates of immunological protection from HIV infection remain undefined. In December 2010, a meeting of scientists engaged in basic and translational work toward developing HIV-1 vaccines was convened. The goal of this meeting was to discuss current opportunities and optimal approaches for defining correlates of protection, both for ongoing and future HIV-1 vaccine candidates; specific efforts were made to engage young scientists. We discuss here the highlights from the meeting regarding the progress made and the way forward for a protective HIV-1 vaccine.

Indexed as

AIDS VaccinesImmunologic MemoryVaccines, SyntheticFemaleGenetic VectorsHIV-1HIV SeropositivityHumansImmunity, CellularImmunity, MucosalMaleT-LymphocytesAIDS VaccinesVaccines, Synthetic

Identifiers

PMID21861777
PMCPMC3380381
OpenAlexW2131790448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.