ArticleEndocrine2011
Erectile dysfunction can improve the effectiveness of the current guidelines for the screening for asymptomatic coronary artery disease in diabetes.
Article in Endocrine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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27 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Erectile dysfunction and cardiovascular events in diabetic men: a meta-analysis of observational studies.PloS one · 2012Pooled it
- Trial
- [Erectile dysfunction-It is time to act! : Practical tips and current guideline recommendations for diagnostics and treatment of a still underestimated disease].Urologie (Heidelberg, Germany) · 2026Article
- Erectile dysfunction, type 2 diabetes, and cardiovascular disease: a narrative review and insights from a global real-world cohort analysis.Frontiers in clinical diabetes and healthcare · 2026Review
- Quality of Chatbot Responses to the Most Popular Questions Regarding Erectile Dysfunction.Urology research & practice · 2025Article
- Erectile Dysfunction: Expert Panel Recommendations for Evaluation and Management in the United Arab Emirates.Journal of multidisciplinary healthcare · 2025Article
- Association between clitoral tissue perfusion and female sexual dysfunction in healthy women of reproductive age: a pilot study.International journal of impotence research · 2020Article
- Article
- Anti-diabetic agents and heart health: how to use new diabetes medications in a global strategy for the prevention of cardiovascular complications in type 2 diabetes.Annals of translational medicine · 2018Article
- Effects of Vitamin D Restricted Diet Administered during Perinatal and Postnatal Periods on the Penis of Wistar Rats.BioMed research international · 2018Article
- Relation Between Erectile Dysfunction and Silent Myocardial Ischemia in Diabetic Patients: A Multidetector Computed Tomographic Coronary Angiographic Study.Sexual medicine · 2016Article
- Erectile dysfunction as a predictor of asymptomatic coronary artery disease in elderly men with type 2 diabetes.Journal of geriatric cardiology : JGC · 2016Article
- Article
- Structured therapeutic education in diabetes: is it time to re-write the chapter on the prevention of diabetic complications?Endocrine · 2016Article
- The role of patient education in the prevention and management of type 2 diabetes: an overview.Endocrine · 2016Review
- Inverse association between serum total bilirubin levels and diabetic peripheral neuropathy in patients with type 2 diabetes.Endocrine · 2015Article
- Endocrine evaluation of erectile dysfunction.Endocrine · 2014Review
- Serum levels of 25-hydroxyvitamin D are associated with cognitive impairment in type 2 diabetic adults.Endocrine · 2014Article
- Review
- Transcutaneous oxygen tension as a potential predictor of cardiovascular events in type 2 diabetes: comparison with ankle-brachial index.Diabetes care · 2013Article
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12 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
About 40% of diabetic patients with asymptomatic coronary artery disease (CAD) are missed on the basis of the current screening guidelines. Erectile Dysfunction (ED) is a powerful marker of asymptomatic CAD. Aim of the study is to evaluate whether ED can improve the effectiveness of the current guidelines for the screening of CAD in diabetes. From among 299 consecutive men with newly diagnosed type 2 diabetes without any apparent vascular complication, 293 (mean age 56.6±5.9 years) were enrolled. Among them, 219 did not have myocardial ischemia (NO CAD group) and 74 men had a coronary stenosis angiographically proven (CAD group). Five risk factors (RFs) of the current screening guidelines (hypertension, dyslipidemia, family history for CAD, smoking e micro/macroalbuminuria) and ED were assessed. ED was significantly more prevalent in the CAD than in the NO CAD group (37.8 versus 15.1%; P<0.001) and was a predictor of asymptomatic CAD (OR: 4.4; 95%CI: 2.1-9.0; P<0.001). If ED is added to the list of RFs, it can increase the sensitivity of the current guidelines from 62 to 89%, without a significant variation in specificity (from 60 to 57%). The negative predictive value can increase from 82 to 94%. ED can reduce from 37.84 to 10.81% the percentage of patients with silent CAD missed at the screening. This study first shows that ED can improve the effectiveness in discriminating diabetic men to screen for asymptomatic CAD, when it is added to the list of RFs of the current screening guidelines.
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