Evidence map›Paper›PMID 21861211›Full record

ReviewNeurotoxicity research2012

New strategies in neuroprotection and neurorepair.

Marta C Antonelli, Gilles J Guillemin, Rita Raisman-Vozari, Elaine A Del-Bel, Michael Aschner, Michael A Collins, Yousef Tizabi, Rosario Moratalla, Adrian K West

Open access · greenAbstract readReview
In one paragraph

Review in Neurotoxicity research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Nicotinic Receptor Intervention in Parkinson's Disease: Future Directions.Clinical pharmacology and translational medicine · 2017
    Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 5 countries.

Marta C AntonelliInstituto de Química y Fisicoquímica Biológicas (UBA-CONICET), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, C1113AAD, Buenos Aires, Argentina. mca@ffyb.uba.ar
Gilles J Guillemin
Rita Raisman-Vozari
Elaine A Del-Bel
Michael Aschner
Michael A Collins
Yousef Tizabi
Rosario Moratalla
Adrian K West
Howard University · USInserm · FRInstituto Cajal · ESInstituto de Química y Fisicoquímica Biológicas · ARJohn F. Kennedy Center for the Performing Arts · USLoyola University Chicago · USUniversity of Tasmania · AUUNSW Sydney · AU

Funding

The Howard University SCORE Program Supplemental GrantS06GM008016 · NIGMS · HOWARD UNIVERSITY · PI HEINBOCKEL, THOMAS · 1989 to 2009
$16.1M
Mechanisms of Manganese NeurotoxicityR01ES010563 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 2001 to 2026
$11.9M
Mechanisms of Methylmercury Induced Neuron ToxicityR01ES007331 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 1996 to 2026
$10.6M
Training in Neuroimmunoendocrine Effects of AlcoholT32AA013527 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI CHOUDHRY, MASHKOOR A · 2002 to 2021
$4.4M
HIV-1 protein neurotoxicity and ethanol pre-conditioningR01AA013568 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI COLLINS, MICHAEL A. · 2003 to 2006
$1.2M
NIAAA NIH HHS R01 AA013568NIAAA NIH HHS T32 AA013527NIEHS NIH HHS R01 ES007331NIEHS NIH HHS R01 ES010563NIEHS NIH HHS R01 ES07331NIEHS NIH HHS R01 ES10563NIGMS NIH HHS 2SO6GM08016-39NIGMS NIH HHS S06 GM008016
6 · The paper itself

Abstract

There are currently few clinical strategies in place, which provide effective neuroprotection and repair, despite an intense international effort over the past decades. One possible explanation for this is that a deeper understanding is required of how endogenous mechanisms act to confer neuroprotection. This mini-review reports the proceedings of a recent workshop "Neuroprotection and Neurorepair: New Strategies" (Iguazu Falls, Misiones, Argentina, April 11-13, 2011, Satellite Symposium of the V Neurotoxicity Society Meeting, 2011) in which four areas of active research were identified to have the potential to generate new insights into this field. Topics discussed were (i) metallothionein and other multipotent neuroprotective molecules; (ii) oxidative stress and their signal mediated pathways in neuroregeneration; (iii) neurotoxins in glial cells, and (iv) drugs of abuse with neuroprotective effects.

Indexed as

Central Nervous SystemMetallothioneinNerve RegenerationNeurogliaNeuroprotective AgentsNeurotoxinsOxidative StressSubstance-Related DisordersMetallothioneinNeuroprotective AgentsNeurotoxins

Identifiers

PMID21861211
PMCPMC3243800
OpenAlexW2010804069

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.