Evidence map›Paper›PMID 21861183›Full record

ReviewCellular and molecular life sciences : CMLS2011

Mechanisms of NK cell activation: CD4(+) T cells enter the scene.

Franck Bihl, Claire Germain, Carmelo Luci, Veronique M Braud

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Foods (Basel, Switzerland) · 2024
    Article
  7. Review
  8. STING Protein-Based In Situ Vaccine Synergizes CD4Advanced healthcare materials · 2023
    Article
  9. Article
  10. CD4Journal of virology · 2022
    Article
  11. Review
  12. Article
  13. Th1-Dominant CD4Frontiers in immunology · 2022
    Article
  14. Article
  15. Review
  16. A CD4Journal of virology · 2020
    Article
  17. The opposing roles of CD4Immunology · 2018
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Franck BihlInstitut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique/Université de Nice-Sophia Antipolis, UMR6097, 660, route des Lucioles, 06560 Valbonne, France.
Claire Germain
Carmelo Luci
Veronique M Braud

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells are innate lymphocytes involved in immunosurveillance through their cytotoxic activity and their capacity to secrete inflammatory cytokines. NK cell activation is necessary to initiate effector functions and results from a complex series of molecular and cellular events. We review here the signals that trigger NK cells and discuss recent findings showing that, besides antigen-presenting cells, T cells can play a central role in the initiation of NK cell activation in lymph nodes.

Indexed as

Antigen-Presenting CellsCD4-Positive T-LymphocytesHumansInterleukin-12Interleukin-2Killer Cells, NaturalLymphocyte ActivationInterleukin-12Interleukin-2

Identifiers

PMID21861183
PMCPMC11114938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.