ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2011
The influence of natural variation at the foraging gene on thermotolerance in adult Drosophila in a narrow temperature range.
Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- TheInternational journal of environmental research and public health · 2021Article
- Aggressive behaviours, food deprivation and theRoyal Society open science · 2017Article
- Article
- Inhibition of diuretic stimulation of an insect secretory epithelium by a cGMP-dependent protein kinase.American journal of physiology. Renal physiology · 2013Article
- Gene-environment interplay in Drosophila melanogaster: chronic food deprivation in early life affects adult exploratory and fitness traits.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
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Authors and funding
6 authors.
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Abstract
Poikilothermic organisms such as insects have mechanisms to protect neural function under high temperature stress. Natural variation at the foraging (for) locus of the fruit fly, Drosophila melanogaster, encoding a cGMP-dependent protein kinase (PKG), influences neural thermotolerance in Drosophila larvae. The current study re-examines thermotolerance of adult flies to account for inconsistencies in the documented role of for during hyperthermia. We found that adult for (R) (rover) flies with high PKG activity were incapacitated faster under hyperthermic conditions of 39°C compared to their lower PKG activity counterparts for (s) and for (s2) (sitters), but not at higher temperatures. This indicates that lowered PKG activity promotes tolerance to heat stress, and that the for gene influences thermotolerance for a narrow range of temperatures in adult flies.
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Registered trials
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