ArticleEvidence-based complementary and alternative medicine : eCAM2012
Association of the Apolipoprotein A5 Gene -1131T>C Polymorphism with Serum Lipids in Korean Subjects: Impact of Sasang Constitution.
Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Apolipoprotein A5 gene variants and the risk of coronary heart disease: a case‑control study and meta‑analysis.Molecular medicine reports · 2013Pooled it
- Pooled it
- Machine learning-based prediction of Sasang constitution types using comprehensive clinical information and identification of key features for diagnosis.Integrative medicine research · 2021Article
- Effects of Acupuncture on Lowering Blood Pressure in Postmenopausal Women with Prehypertension or Stage 1 Hypertension: A Propensity Score-Matched Analysis.Journal of clinical medicine · 2021Article
- Analysis of Facial Features according to Sasang Types between Native Japanese and Native Korean Populations.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Body composition and personality traits in so-Yang type males.BMC complementary and alternative medicine · 2017Article
- Genome-Wide Association Study Reveals Four Loci for Lipid Ratios in the Korean Population and the Constitutional Subgroup.PloS one · 2017Article
- The APOA5 rs662799 polymorphism is associated with dyslipidemia and the severity of coronary heart disease in Chinese women.Lipids in health and disease · 2016Article
- Sasang constitution may act as a risk factor for prehypertension.BMC complementary and alternative medicine · 2015Article
- The obesity-risk variant of FTO is inversely related with the So-Eum constitutional type: genome-wide association and replication analyses.BMC complementary and alternative medicine · 2015Article
- Constitutional multicenter bank linked to Sasang constitutional phenotypic data.BMC complementary and alternative medicine · 2015Article
- Best-fit index for describing physical perspectives in Sasang typology.Integrative medicine research · 2015Article
- The prevalence of general and abdominal obesity according to sasang constitution in Korea.BMC complementary and alternative medicine · 2014Article
- Genetic loci associated with changes in lipid levels leading to constitution-based discrepancy in Koreans.BMC complementary and alternative medicine · 2014Article
- Absence of Association between -1131T>C Polymorphism in the Apolipoprotein APOA5 Gene and Pediatric Metabolic Syndrome.Iranian journal of pediatrics · 2014Article
- A practical approach to Sasang constitutional diagnosis using vocal features.BMC complementary and alternative medicine · 2013Article
- Could the Sasang constitution itself be a risk factor of abdominal obesity?BMC complementary and alternative medicine · 2013Article
- Re-interpretation of traditional Asian medicine with constitutional perspective.Integrative medicine research · 2013Review
- Association of apolipoprotein A5 gene -1131T>C polymorphism with the risk of metabolic syndrome in Korean subjects.BioMed research international · 2013Article
- Comparison of Gut Microbiota between Sasang Constitutions.Evidence-based complementary and alternative medicine : eCAM · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apolipoprotein A5 (APOA5) was identified as a strong modulator of serum lipids. Moreover, an APOA5 gene -1131T>C polymorphism has been associated with serum lipids, but the results are inconsistent according to ethnic and racial groups. We have genotyped and analyzed 1,619 outpatients of Korean oriental medicine hospitals who were classified into three Sasang constitution groups (SCGs), So-Yang (SY), So-Eum (SE), and Tae-Eum (TE). There were no significant difference in the distribution of the APOA5 -1131T>C genotype among the three SCGs. Subjects with the C allele in SY and TE showed significantly lower serum high-density lipoprotein cholesterol (HDL-C) and higher triglyceride (TG) levels than noncarriers of the C allele. These results show the differences in the prevalence of decreasing serum HDL-C and elevating serum TG levels along with APOA5 -1131T>C polymorphism according to SCG and suggest that SCG may act as a significant risk factor for hypo-HDL-C-emia and hypertriglyceridemia susceptibility.
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Registered trials
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