Evidence map›Paper›PMID 21859918›Full record

ArticlePediatrics2011

Ethnic variability in persistent asthma after in utero tobacco exposure.

Kwei Akuete, Sam S Oh, Shannon Thyne, Jose R Rodriguez-Santana, Rocio Chapela, Kelley Meade, William Rodriguez-Cintron, Michael LeNoir, Jean G Ford, L Keoki Williams and 3 more

Abstract read
In one paragraph

Article in Pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Asthma in Hispanics. An 8-year update.American journal of respiratory and critical care medicine · 2014
    Review
  8. Effect of secondhand smoke on asthma control among black and Latino children.The Journal of allergy and clinical immunology · 2012
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 5 countries.

Kwei AkueteDepartment of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Sam S Oh
Shannon Thyne
Jose R Rodriguez-Santana
Rocio Chapela
Kelley Meade
William Rodriguez-Cintron
Michael LeNoir
Jean G Ford
L Keoki Williams
Pedro C Avila
Esteban González Burchard
Haig Tcheurekdjian
Case Western Reserve University · USCardiovascular Institute Hospital · JPCentro de Neumologia Pediatrica · PRHenry Ford Health System · USInstituto Nacional de Enfermedades Respiratorias · MXJohns Hopkins University · USKIPP Bay Area Schools · USNorthwestern University · USSan Francisco General Hospital · USUniversity of California, San Francisco · USVA Caribbean Healthcare System · PR

Funding

Understanding Asthma EndotypesU19AI077439 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI David J Erle · 2008 to 2026
$41.1M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
Postdoctoral training in tobacco controlR25CA113710 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GLANTZ, STANTON ARNOLD · 2006 to 2015
$5.4M
Whole Genome Analyses for Asthma in Latino PopulationsR01HL088133 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$3.8M
Postdoctoral training in tobacco controlT32CA113710 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LING, PAMELA MAY · 2016 to 2020
$2.6M
Case-control Association Studies and Genetic ConfoundingR01HL078885 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2005 to 2009
$1.9M
NCI NIH HHS CA-113710NCI NIH HHS R25 CA113710NCI NIH HHS T32 CA113710NHLBI NIH HHS HL078885NHLBI NIH HHS HL088133NHLBI NIH HHS R01 HL078885NHLBI NIH HHS R01 HL088133NIAID NIH HHS AI077439NIAID NIH HHS U19 AI077439NIEHS NIH HHS R01 ES015794
6 · The paper itself

Abstract

backgroundThe effects of in utero tobacco smoke exposure on childhood respiratory health have been investigated, and outcomes have been inconsistent.

objectiveTo determine if in utero tobacco smoke exposure is associated with childhood persistent asthma in Mexican, Puerto Rican, and black children. PATIENTS AND

methodsThere were 295 Mexican, Puerto Rican, and black asthmatic children, aged 8 to 16 years, who underwent spirometry, and clinical data were collected from the parents during a standardized interview. The effect of in utero tobacco smoke exposure on the development of persistent asthma and related clinical outcomes was evaluated by logistic regression.

resultsChildren with persistent asthma had a higher odds of exposure to in utero tobacco smoke, but not current tobacco smoke, than did children with intermittent asthma (odds ratio [OR]: 3.57; P = .029). Tobacco smoke exposure from parents in the first 2 years of life did not alter this association. Furthermore, there were higher odds of in utero tobacco smoke exposure in children experiencing nocturnal symptoms (OR: 2.77; P = .048), daily asthma symptoms (OR: 2.73; P = .046), and emergency department visits (OR: 3.85; P = .015) within the year.

conclusionsExposure to tobacco smoke in utero was significantly associated with persistent asthma among Mexican, Puerto Rican, and black children compared with those with intermittent asthma. These results suggest that smoking cessation during pregnancy may lead to a decrease in the incidence of persistent asthma in these populations.

Indexed as

AdultAsthmaBlack or African AmericanChildFemaleHispanic or LatinoHumansLogistic ModelsMaternal WelfareMexican AmericansPregnancyPrenatal Exposure Delayed EffectsPuerto RicoSmokingTobacco Smoke PollutionTobacco Smoke Pollution

Identifiers

PMID21859918
PMCPMC3164096
OpenAlexW2010731741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.