Evidence map›Paper›PMID 21859476›Full record

ArticleGenome biology2011

Cistrome: an integrative platform for transcriptional regulation studies.

Tao Liu, Jorge A Ortiz, Len Taing, Clifford A Meyer, Bernett Lee, Yong Zhang, Hyunjin Shin, Swee S Wong, Jian Ma, Ying Lei and 7 more

Registry-linked trialAbstract read
In one paragraph

Article in Genome biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04031716 (Genetic, Epigenetic, Psychosocial, and Biological Determinants of Post-surgical Pain After Pectus or Spine Surgery), which is not on this map. Cited by 479 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
479citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04031716 naactive not recruitingnot on this mapstarted 2018, after this paper: background citation

Genetic, Epigenetic, Psychosocial, and Biological Determinants of Post-surgical Pain After Pectus or Spine Surgery

TypeinterventionalSponsorChildren's Hospital Medical Center, CincinnatiRan2018 to 2025Enrolled600ConditionsPain, Postoperative, Excavatum, Pectus, Scoliosis IdiopathicArmsMeditation
3 · Its place in the literature

Who cites it

479 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Genes · 2020
    Pooled it
  2. Pooled it
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  18. HBMC bioinformatics · 2025
    Article
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  20. bioRxiv : the preprint server for biology · 2025
    Article

419 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tao LiuDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard School of Public Health, Boston, MA 02215, USA.
Jorge A Ortiz
Len Taing
Clifford A Meyer
Bernett Lee
Yong Zhang
Hyunjin Shin
Swee S Wong
Jian Ma
Ying Lei
Utz J Pape
Michael Poidinger
Yiwen Chen
Kevin Yeung
Myles Brown
Yaron Turpaz
X Shirley Liu

Funding

ProteomicsU19DK062434 · NIDDK · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI QIN, JUN · 2002 to 2011
$37.4M
Computational Models for Mechanisms of Global Transcription RegulationR01HG004069 · NHGRI · DANA-FARBER CANCER INST · PI LIU, XIAOLE SHIRLEY · 2006 to 2013
$3.6M
Comprehensive Analysis of Estrogen Receptor Genomic ActionR01DK074967 · NIDDK · DANA-FARBER CANCER INST · PI BROWN, MYLES A · 2007 to 2011
$2.9M
Comprehensive Analysis of Estrogen Receptor Genomic ActionR56DK074967 · NIDDK · DANA-FARBER CANCER INST · PI BROWN, MYLES A · 2006 to 2006
$420k
NHGRI NIH HHS HG004069-04S1NIDDK NIH HHS DK062434NIDDK NIH HHS DK074967
6 · The paper itself

Abstract

The increasing volume of ChIP-chip and ChIP-seq data being generated creates a challenge for standard, integrative and reproducible bioinformatics data analysis platforms. We developed a web-based application called Cistrome, based on the Galaxy open source framework. In addition to the standard Galaxy functions, Cistrome has 29 ChIP-chip- and ChIP-seq-specific tools in three major categories, from preliminary peak calling and correlation analyses to downstream genome feature association, gene expression analyses, and motif discovery. Cistrome is available at http://cistrome.org/ap/.

Indexed as

Gene Expression RegulationSoftwareChromatin ImmunoprecipitationComputational BiologyDatabases, GeneticHumansInternetOligonucleotide Array Sequence AnalysisTranscription FactorsTranscription Factors

Identifiers

PMID21859476
PMCPMC3245621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.