ArticleThe protein journal2011
Molecular cloning, sequence characterization, and tissue expression analysis of Hi-Line Brown chicken Akirin2.
Article in The protein journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Role of akirin in skeletal myogenesis.International journal of molecular sciences · 2013Article
Corrections and comments
- Retraction · 2012-02-10Duplication of Text · Plagiarism of Text ·
- Retracted
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Akirins are novel important nuclear proteins able to modulate transcriptional activities in a gene-specific manner. Akirin2 is an important gene related to immune responses, it is necessary to isolate the akirin2 gene from chicken because it may be associated with vaccine and enhancement of immune response. In this study, a Hi-Line Brown chicken homolog of the vertebrate akirin2 gene was cloned, sequenced, and characterized. The akirin2 full-length coding sequence (CDS) consisted of 576nt and encoded 191 amino acids with a molecular weight of 21.58 kD. The COOH-terminal alpha-helix region was well conserved between chicken and other animals. RT-PCR analysis showed that the akirin2 transcripts were constitutively expressed in 16 tissues tested. Several microRNA target sites were predicted in the CDS of chicken akirin2 gene. We presume that Akirin2 protein may be used as a new-type immunopotentiator in poultry immune system in the future.
Indexed as
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Registered trials
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