Evidence map›Paper›PMID 21858562›Full record

ReviewDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2011

[Indications and evidence base for specific immunotherapy in childhood].

H Ott, A Bufe, H F Merk

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Diseases of the nose and paranasal sinuses in child.GMS current topics in otorhinolaryngology, head and neck surgery · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

H OttAbt. Pädiatrische Dermatologie und Allergologie, Kath. Kinderkrankenhaus Wilhelmstift, Hamburg, Deutschland. h.ott@kkh-wilhelmstift.de
A Bufe
H F Merk
Katholisches Kinderkrankenhaus Wilhelmstift · DERuhr University Bochum · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR) is a common disease affecting 7-17% of children and adolescents who may suffer from a significantly impaired quality of life. For 100 years subcutaneous immunotherapy (SCIT) has been used to treat AR. If patients are chosen carefully, a clinically relevant reduction of seasonal symptoms and medication use can be achieved by SCIT. Serious adverse events are rarely encountered during adequately performed and monitored SCIT. Sublingual immunotherapy (SLIT) may be used as a less painful therapeutic alternative in children if the administration of SCIT is impossible. Recent controlled trials have shown that SLIT performed over one pollen season also ameliorates seasonal symptoms and reduces the need for concomitant medication. Local reactions are frequently encountered during SLIT whereas systemic and life-threatening adverse events under correctly performed SLIT have not been reported so far.

Indexed as

Administration, SublingualAdolescentAnaphylaxisAnti-Allergic AgentsChildCombined Modality TherapyContraindicationsDesensitization, ImmunologicEpitopesEvidence-Based MedicineHumansImmune ToleranceImmunoglobulin EInjections, SubcutaneousRandomized Controlled Trials as TopicRhinitis, Allergic, PerennialAnti-Allergic AgentsEpitopesImmunoglobulin E

Identifiers

PMID21858562
OpenAlexW173481476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.