ArticleIntensive care medicine2011
Optimal duration of a sustained inflation recruitment maneuver in ARDS patients.
Article in Intensive care medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05508724 (An Observational Study of the Relationship Between Pressure-volume Curves and Recruitability of the Lung in Mechanically Ventilated Critically Ill Patients With Respiratory Failure), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Observational Study of the Relationship Between Pressure-volume Curves and Recruitability of the Lung in Mechanically Ventilated Critically Ill Patients With Respiratory Failure
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Tidal volume and plateau pressure use for acute lung injury from 2000 to present: a systematic literature review.Critical care medicine · 2014Pooled it
- Ventilator-Induced Signal Interference and the Accuracy of the Pressure Reactivity Index in Acute Brain Injury.Neurocritical care · 2026Article
- Comparison of two different recruitment maneuver patterns in ARDS patients.Intensive care medicine experimental · 2026Article
- Positive end-expiratory pressure titration in acute respiratory distress syndrome-a practical bedside algorithm.Frontiers in medicine · 2026Review
- Managing Refractory Hypoxemia in Acute Respiratory Distress Syndrome Obese Patients with Veno-Venous Extra-Corporeal Membrane Oxygenation: A Narrative Review.Journal of clinical medicine · 2025Review
- Is "Optimized Recruitment" Really Worth the Effort?Respiratory care · 2024Article
- Management of severe acute respiratory distress syndrome: a primer.Critical care (London, England) · 2023Review
- Acute Respiratory Distress Syndrome, Mechanical Ventilation, and Inhalation Injury in Burn Patients.The Surgical clinics of North America · 2023Review
- Management of refractory hypoxemia using recruitment maneuvers and rescue therapies: A comprehensive review.Frontiers in veterinary science · 2023Review
- High Positive End-Expiratory Pressure and Lung Recruitment in Moderate to Severe Acute Respiratory Distress Syndrome: Does One Size Really Fit All?American journal of respiratory and critical care medicine · 2022Article
- Lung Mechanics of Mechanically Ventilated Patients With COVID-19: Analytics With High-Granularity Ventilator Waveform Data.Frontiers in medicine · 2020Article
- The Contribution of Surface Tension-Dependent Alveolar Septal Stress Concentrations to Ventilation-Induced Lung Injury in the Acute Respiratory Distress Syndrome.Frontiers in physiology · 2020Article
- Effects of SI and PCV on respiratory mechanics, early central drive and hemodynamics in patients with ARDS.Experimental and therapeutic medicine · 2019Article
- Should we titrate positive end-expiratory pressure based on an end-expiratory transpulmonary pressure?Annals of translational medicine · 2018Article
- Recruitment maneuvers in acute respiratory distress syndrome.Annals of translational medicine · 2017Review
- Article
- Recruitment maneuvers in acute respiratory distress syndrome: The safe way is the best way.World journal of critical care medicine · 2015Review
- Dynamics of end expiratory lung volume after changing positive end-expiratory pressure in acute respiratory distress syndrome patients.Critical care (London, England) · 2015Article
- Effect of Repeated Recruitment Manoeuvres on Patients with Severe Acute Respiratory Distress Syndrome.The West Indian medical journal · 2015Article
- Effects of basic drugs on prognosis of acute lung injury in mice.International journal of clinical and experimental medicine · 2015Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo measure the dynamics of recruitment and the hemodynamic status during a sustained inflation recruitment maneuver (RM) in order to determine the optimal duration of RM in acute respiratory distress syndrome (ARDS) patients.
methodsThis prospective study was conducted in a 12-bed intensive care unit (ICU) in a general hospital. A 40 cmH(2)O sustained inflation RM maintained for 30 s was performed in 50 sedated ventilated patients within the first 24 h of meeting ARDS criteria. Invasive arterial pressures, heart rate, and SpO(2) were measured at 10-s intervals during the RM. The volume increase during the RM was measured by integration of the flow required to maintain the pressure at 40 cmH(2)O, which provides an estimation of the volume recruited during the RM. Raw data were corrected for gas consumption and fitted with an exponential curve in order to determine an individual time constant for the volume increase.
resultsThe average volume increase and time constant were 210 ± 198 mL and 2.3 ± 1.3 s, respectively. Heart rate, diastolic arterial pressure, and SpO(2) did not change during or after the RM. Systolic and mean arterial pressures were maintained at 10 s, decreased significantly at 20 and 30 s during the RM, and recovered to the pre-RM value 30 s after the end of the RM (ANOVA, p < 0.01).
conclusionsIn early-onset ARDS patients, most of the recruitment occurs during the first 10 s of a sustained inflation RM. However, hemodynamic impairment is significant after the tenth second of RM.
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