ArticleParasitology research2012
Larvicidal activity of lignans from Phryma leptostachya L. against Culex pipiens pallens.
Article in Parasitology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Machine learning optimized callogenesis in Justicia gendarussa Burm. f. and phytochemical profiling of in vitro derived callus and leaf extracts.BMC biotechnology · 2026Article
- Identification and functional characterization of the dirigent gene family in Phryma leptostachya and the contribution of PlDIR1 in lignan biosynthesis.BMC plant biology · 2023Article
- The Mosquito Larvicidal Activity of Lignans from Branches ofMolecules (Basel, Switzerland) · 2023Article
- A Synthetic View on Haedoxans and Related Neolignans FromFrontiers in chemistry · 2020Review
- Insecticidal Activity of Four Lignans Isolated fromMolecules (Basel, Switzerland) · 2019Article
- Larvicidal and ovicidal activity ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2017Article
- Bioefficacy of ecbolin A and ecbolin B isolated fromParasite epidemiology and control · 2016Article
- Article
- Tea polyphenols ameliorate fat storage induced by high-fat diet inBiochemistry and biophysics reports · 2015Article
- Toxicity of amorphigenin from the seeds of Amorpha fruticosa against the larvae of Culex pipiens pallens (Diptera: Culicidae).Molecules (Basel, Switzerland) · 2015Article
- Larvicidal and pupicidal activities of ecbolin A and ecbolin B isolated from Ecbolium viride (Forssk.) Alston against Culex quinquefasciatus Say (Diptera: Culicidae).Parasitology research · 2014Article
- Article
- Synthesis and larvicidal activity against Culex pipiens pallens of new triazole derivatives of phrymarolin from Phryma leptostachya L.International journal of molecular sciences · 2013Article
- Larvicidal activity of lansiumamide B from the seeds of Clausena lansium against Aedes albopictus (Diptera: Culicidae).Parasitology research · 2013Article
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5 authors.
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Abstract
The larvicidal activity of crude petroleum ether, ethyl acetate, and methanol extracts of the whole plants of Phryma leptostachya L. was assayed for its toxicity against the early fourth instar larvae of Culex pipiens pallens. The larval mortality was observed after 24 h of exposure. Among three solvent extracts from Phyrma leptostachya L., the petroleum ether extract exhibited the best larvicidal activity. The corresponding LC₅₀ values of petroleum ether, ethyl acetate, and methanol extracts were 3.23, 5.23, and 61.86 ppm against the early fourth instar larvae of Culex pipiens pallens. The petroleum ether extract was successively subjected to column chromatography and preparative high performance liquid chromatography, and yielded the three lignans, phrymarolin-I, haedoxane A, and haedoxane E, which were isolated and identified as new mosquito larvicidal compounds. Phrymarolin-I, haedoxane A, and haedoxane E showed high larvicidal activity, for which the lethal doses LC₅₀ were estimated at 1.21, 0.025, and 0.15 ppm against the early fourth instar larvae of Culex pipiens pallens, respectively. The structures were elucidated by analyses of IR, UV, MS, and NMR spectral data. This is the first report on the mosquito larvicidal activity of the three compounds, phrymarolin-I, haedoxane A, and haedoxane E from Phyrma leptostachya L.
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