ArticlePloS one2011
Diffuse and specific tectopulvinar terminals in the tree shrew: synapses, synapsins, and synaptic potentials.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- A conserved pulvinar projection to the amygdala revealed in macaque monkeys (Macaca mulatta).Brain structure & function · 2026Article
- CBLN2 promoter enables genetic access to wide-field neurons of the tree shrew superior colliculus.Cell reports methods · 2026Article
- Individual Pulvinar Neurons Integrate Cortical and Subcortical Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Ultrastructure of ipsilateral and contralateral tectopulvinar projections in the mouse.The Journal of comparative neurology · 2022Article
- Article
- Synaptic organization of the dorsal lateral geniculate nucleus.The European journal of neuroscience · 2019Review
- Ultrastructural and optogenetic dissection of V1 corticotectal terminal synaptic properties.The Journal of comparative neurology · 2019Article
- The Second Visual System of The Tree Shrew.The Journal of comparative neurology · 2019Review
- The mouse pulvinar nucleus: Organization of the tectorecipient zones.Visual neuroscience · 2017Review
- Ultrastructure of geniculocortical synaptic connections in the tree shrew striate cortex.The Journal of comparative neurology · 2016Article
- Distributions of vesicular glutamate transporters 1 and 2 in the visual system of tree shrews (Tupaia belangeri).The Journal of comparative neurology · 2015Article
- Retinal and Tectal "Driver-Like" Inputs Converge in the Shell of the Mouse Dorsal Lateral Geniculate Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Thalamic Circuit Diversity: Modulation of the Driver/Modulator Framework.Frontiers in neural circuits · 2015Review
- Terminals of the major thalamic input to visual cortex are devoid of synapsin proteins.Neuroscience · 2013Article
- Cortical projections to the superior colliculus in tree shrews (Tupaia belangeri).The Journal of comparative neurology · 2013Article
- Morphological and neurochemical comparisons between pulvinar and V1 projections to V2.The Journal of comparative neurology · 2013Article
- Chronic clomipramine treatment reverses core symptom of depression in subordinate tree shrews.PloS one · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The pulvinar nucleus of the tree shrew receives both topographic (specific) and nontopographic (diffuse) projections from superior colliculus (SC), which form distinct synaptic arrangements. We characterized the physiological properties of these synapses and describe two distinct types of excitatory postsynaptic potentials (EPSPs) that correlate with structural properties of the specific and diffuse terminals. Synapses formed by specific terminals were found to be significantly longer than those formed by diffuse terminals. Stimulation of these two terminal types elicited two types of EPSPs that differed in their latency and threshold amplitudes. In addition, in response to repetitive stimulation (0.5-20 Hz) one type of EPSP displayed frequency-dependent depression whereas the amplitudes of the second type of EPSP were not changed by repetitive stimulation of up to 20 Hz. To relate these features to vesicle release, we compared the synapsin content of terminals in the pulvinar nucleus and the dorsal lateral geniculate (dLGN) by combining immunohistochemical staining for synapsin I or II with staining for the type 1 or type 2 vesicular glutamate transporters (markers for corticothalamic and tectothalamic/retinogeniculate terminals, respectively). We found that retinogeniculate terminals do not contain either synapsin I or synapsin II, corticothalamic terminals in the dLGN and pulvinar contain synapsin I, but not synapsin II, whereas tectopulvinar terminals contain both synapsin I and synapsin II. Finally, both types of EPSPs showed a graded increase in amplitude with increasing stimulation intensity, suggesting convergence; this was confirmed using a combination of anterograde tract tracing and immunocytochemistry. We suggest that the convergent synaptic arrangements, as well as the unique synapsin content of tectopulvinar terminals, allow them to relay a dynamic range of visual signals from the SC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.