ArticlePloS one2011
Dramatic transcriptional changes in an intracellular parasite enable host switching between plant and insect.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 93 citations in OpenAlex.
- Dual RNA-seq reveals the global transcriptome ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Definition of the effector landscape across 13 phytoplasma proteomes with LEAPH and EffectorComb.NAR genomics and bioinformatics · 2024Article
- Use of the 23S rRNA gene as a target template in the universal loop-mediated isothermal amplification (LAMP) of genomic DNA from phytoplasmas.Microbiology spectrum · 2024Article
- The Antigenic Membrane Protein (Amp) of Rice Orange Leaf Phytoplasma Suppresses Host Defenses and Is Involved in Pathogenicity.International journal of molecular sciences · 2023Article
- The Complete Genome of the "Flavescence Dorée" Phytoplasma Reveals Characteristics of Low Genome Plasticity.Biology · 2022Article
- Plants and Phytoplasmas: When Bacteria Modify Plants.Plants (Basel, Switzerland) · 2022Review
- Differences in Gene Expression of Pear Selections Showing Leaf Curling or Leaf Reddening Symptoms Due to Pear Decline Phytoplasma.Plants (Basel, Switzerland) · 2022Article
- Accelerating Complete Phytoplasma Genome Assembly by Immunoprecipitation-Based Enrichment and MinION-Based DNA Sequencing for Comparative Analyses.Frontiers in microbiology · 2021Article
- Spatiotemporal dynamics and quantitative analysis of phytoplasmas in insect vectors.Scientific reports · 2020Article
- Flavescence Dorée Phytoplasma Has MultipleInternational journal of molecular sciences · 2019Article
- Molecular and biological properties of phytoplasmas.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2019Review
- Two Phytoplasmas Elicit Different Responses in the Insect Vector Euscelidius variegatus Kirschbaum.Infection and immunity · 2018Article
- Functional characterization of LotP from Liberibacter asiaticus.Microbial biotechnology · 2017Article
- Invasive mutualisms between a plant pathogen and insect vectors in the Middle East and Brazil.Royal Society open science · 2016Article
- Harnessing Host-Vector Microbiome for Sustainable Plant Disease Management of Phloem-Limited Bacteria.Frontiers in plant science · 2016Review
- 'Candidatus Phytoplasma phoenicium' associated with almond witches'-broom disease: from draft genome to genetic diversity among strain populations.BMC microbiology · 2015Article
- Functional characterization of the principal sigma factor RpoD of phytoplasmas via an in vitro transcription assay.Scientific reports · 2015Article
- Decreasing global transcript levels over time suggest that phytoplasma cells enter stationary phase during plant and insect colonization.Applied and environmental microbiology · 2015Article
- Degradation of class E MADS-domain transcription factors in Arabidopsis by a phytoplasmal effector, phyllogen.Plant signaling & behavior · 2015Article
- RNA-Seq profile of flavescence dorée phytoplasma in grapevine.BMC genomics · 2014Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phytoplasmas are bacterial plant pathogens that have devastating effects on the yields of crops and plants worldwide. They are intracellular parasites of both plants and insects, and are spread among plants by insects. How phytoplasmas can adapt to two diverse environments is of considerable interest; however, the mechanisms enabling the "host switching" between plant and insect hosts are poorly understood. Here, we report that phytoplasmas dramatically alter their gene expression in response to "host switching" between plant and insect. We performed a detailed characterization of the dramatic change that occurs in the gene expression profile of Candidatus Phytoplasma asteris OY-M strain (approximately 33% of the genes change) upon host switching between plant and insect. The phytoplasma may use transporters, secreted proteins, and metabolic enzymes in a host-specific manner. As phytoplasmas reside within the host cell, the proteins secreted from phytoplasmas are thought to play crucial roles in the interplay between phytoplasmas and host cells. Our microarray analysis revealed that the expression of the gene encoding the secreted protein PAM486 was highly upregulated in the plant host, which is also observed by immunohistochemical analysis, suggesting that this protein functions mainly when the phytoplasma grows in the plant host. Additionally, phytoplasma growth in planta was partially suppressed by an inhibitor of the MscL osmotic channel that is highly expressed in the plant host, suggesting that the osmotic channel might play an important role in survival in the plant host. These results also suggest that the elucidation of "host switching" mechanism may contribute to the development of novel pest controls.
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