ArticlePloS one2011
Characterization of the small RNA transcriptome of the diatom, Thalassiosira pseudonana.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 39 citations in OpenAlex.
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- Comparative in depth RNA sequencing of P. tricornutum's morphotypes reveals specific features of the oval morphotype.Scientific reports · 2018Article
- Analysis of Small RNAs in Streptococcus mutans under Acid Stress-A New Insight for Caries Research.International journal of molecular sciences · 2016Article
- Characterization of the Small RNA Transcriptome of the Marine Coccolithophorid, Emiliania huxleyi.PloS one · 2016Article
- Diverse Evolutionary Trajectories for Small RNA Biogenesis Genes in the Oomycete Genus Phytophthora.Frontiers in plant science · 2016Article
- Widespread occurrence of organelle genome-encoded 5S rRNAs including permuted molecules.Nucleic acids research · 2014Article
- Global discovery and characterization of small non-coding RNAs in marine microalgae.BMC genomics · 2014Article
- Article
- Polar Microalgae: New Approaches towards Understanding Adaptations to an Extreme and Changing Environment.Biology · 2014Article
- Biochemical and genetic engineering of diatoms for polyunsaturated fatty acid biosynthesis.Marine drugs · 2014Review
- RNA function and phosphorus use by photosynthetic organisms.Frontiers in plant science · 2013Review
- Phenotypic diversification by gene silencing in Phytophthora plant pathogens.Communicative & integrative biology · 2013Review
- Comparison of microRNA deep sequencing of matched formalin-fixed paraffin-embedded and fresh frozen cancer tissues.PloS one · 2013Article
- Evidence for widespread exonic small RNAs in the glaucophyte alga Cyanophora paradoxa.PloS one · 2013Article
- Evidence for small RNAs homologous to effector-encoding genes and transposable elements in the oomycete Phytophthora infestans.PloS one · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study presents the first characterization of endogenous small RNAs in a diatom, Thalassiosira pseudonana. Small RNAs act as transcriptional and translational regulators, controlling specific target genes involved in various cellular functions. Diatoms are unicellular photosynthetic organisms that play major roles in environmental processes, such as food webs and global carbon fixation. Small RNA cDNA libraries were constructed for exponentially growing T. pseudonana, and then subjected to highly parallel pyrosequencing (454) and sequencing-by-ligation (Applied Biosystems SOLiD). From the computational analysis of approximately 300,000 sequences in the 454 library and over 17 million sequences in the SOLiD libraries, there exists evidence of a core set of small RNA genes including: novel microRNAs, repeat-associated short interfering RNAs, and endogenous short interfering RNAs. The diatom genome contains elements similar to plant small RNA systems, such as the RNAi machinery, a high percentage of short interfering RNAs originating from protein-coding and repetitive regions of the genome, and putative binding sites of the small RNAs occurring primarily in the coding section of the predicted targets. The characterization of the small RNA transcriptome of T. pseudonana establishes the possibility of a wide range of gene regulatory mechanisms in diatoms.
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