Evidence map›Paper›PMID 21857797›Full record

ArticleCrystal growth & design2011

Inorganic-Organic Nanocomposite Assembly Using Collagen as Template and Sodium Tripolyphosphate as A Biomimetic Analog of Matrix Phosphoprotein.

Lin Dai, Yi-Pin Qi, Li-Na Niu, Yan Liu, Cesar R Pucci, Stephen W Looney, Jun-Qi Ling, David H Pashley, Franklin R Tay

Abstract read
In one paragraph

Article in Crystal growth & design, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. [Effects of different polymers on biomimetic mineralization of small intestine submucosal scaffolds].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024
    Article
  3. Article
  4. In Vitro Mineralization of Collagen.Advanced materials (Deerfield Beach, Fla.) · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Biomimetic remineralization of dentin.Dental materials : official publication of the Academy of Dental Materials · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Lin DaiDepartment of Stomatology, The First Hospital of Wuhan, Wuhan (China).
Yi-Pin Qi
Li-Na Niu
Yan Liu
Cesar R Pucci
Stephen W Looney
Jun-Qi Ling
David H Pashley
Franklin R Tay
Sun Yat-sen University · CNAir Force Medical University · CNAmerican Association of Endodontists · USBiostats (United States) · USPeking University · CNUniversidade Estadual Paulista (Unesp) · BRWuhan No.1 Hospital · CN

Funding

Biomimetic remineralization of resin-dentin bondsR21DE019213 · NIDCR · AUGUSTA UNIVERSITY · PI TAY, FRANKLIN CHI MENG · 2009 to 2010
$362k
NIDCR NIH HHS R21 DE019213
6 · The paper itself

Abstract

Nanocomposites created with polycarboxylic acid alone as a stabilization agent for prenucleation clusters-derived amorphous calcium phosphate exhibit non-periodic apatite deposition. In the present study, we report the use of inorganic polyphosphate as a biomimetic analog of matrix phosphoprotein for directing polyacrylic acid-stabilized amorphous nanoprecursor phases to assemble into periodic apatite-collagen nanocomposites. The sorption and desorption characteristics of sodium tripolyphosphate to type I collagen was examined. Periodic nanocomposite assembly with collagen as a template was demonstrated with TEM and SEM using a Portland cement-based resin composite and a phosphate-containing simulated body fluid. Apatite was detected within the collagen at 24 hours and became more distinct at 48 hours, with prenucleation clusters attaching to the collagen fibril surface during the initial infiltration stage. Apatite-collagen nanocomposites at 72 hours were heavily mineralized with periodically-arranged intrafibrillar apatite platelets. Defect-containing nanocomposites caused by desorption of TPP from collagen fibrils were observed in regions lacking the inorganic phase.

Identifiers

PMID21857797
PMCPMC3156482
OpenAlexW2131402010

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.