Evidence map›Paper›PMID 21857517›Full record

Trial reportEar and hearing

Ear-canal reflectance, umbo velocity, and tympanometry in normal-hearing adults.

John J Rosowski, Hideko H Nakajima, Mohamad A Hamade, Lorice Mahfoud, Gabrielle R Merchant, Christopher F Halpin, Saumil N Merchant

Abstract readClinical TrialComparative StudyValidation Study
In one paragraph

Trial report in Ear and hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 100 citations in OpenAlex.

  1. Power reflectance as a screening tool for the diagnosis of superior semicircular canal dehiscence.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2015
    Trial
  2. Trial
  3. The UmboMic: Characterization and Testing of a Middle Ear Microphone.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Article
  4. Article
  5. Restoration of High-Frequency Middle Ear Function in Partial Ossicular Discontinuity: A Basic Science and Clinical Correlation.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026
    Article
  6. The Transmission of Sound to the Cochlea in Normal and Pathological Human Middle Ears.Journal of the Association for Research in Otolaryngology : JARO · 2025
    Review
  7. Article
  8. The UmboMic: A PVDF Cantilever Microphone.Journal of micromechanics and microengineering : structures, devices, and systems · 2024
    Article
  9. Article
  10. Measuring absorbed energy in the human auditory system using finite element models: A comparison with experimental results.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  11. Wideband Tympanometry (WBT) Features in Children with Cleft Palate and Otitis Media with Effusion Before and After Cleft Palate Surgery.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Mechanics of Total Drum Replacement Tympanoplasty Studied With Wideband Acoustic Immittance.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2022
    Article
  16. Article
  17. Study on wideband tympanometry and absorbance within a Danish cohort of normal hearing adults.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

John J RosowskiEaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA. john_rosowski@meei.harvard.edu
Hideko H Nakajima
Mohamad A Hamade
Lorice Mahfoud
Gabrielle R Merchant
Christopher F Halpin
Saumil N Merchant
Massachusetts Eye and Ear Infirmary · US

Funding

STRUCTURE/FUNCTION RELATIONS IN MIDDLE EARSR01DC000194 · NIDCD · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ROSOWSKI, JOHN J · 1989 to 2018
$5.9M
Middle-ear Mechanics in Normal and Pathological EarsR01DC004798 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI NAKAJIMA, HIDEKO HEIDI · 2001 to 2016
$4.9M
NIDCD NIH HHS R01 DC000194NIDCD NIH HHS R01 DC004798NIDCD NIH HHS R01-DC004798
6 · The paper itself

Abstract

objectiveThis study compares measurements of ear-canal reflectance (ECR) to other objective measurements of middle ear function including audiometry, umbo velocity (VU), and tympanometry in a population of strictly defined normal-hearing ears.

designData were prospectively gathered from 58 ears of 29 normal-hearing subjects, 16 females and 13 males, aged 22 to 64 yr. Subjects met all of the following criteria to be considered as having normal hearing: (1) no history of significant middle ear disease; (2) no history of otologic surgery; (3) normal tympanic membrane on otoscopy; (4) pure-tone audiometric thresholds of 20 dB HL or better for 0.25 to 8 kHz; (5) air-bone gaps no greater than 15 dB at 0.25 kHz and 10 dB for 0.5 to 4 kHz; (6) normal, type-A peaked tympanograms; and (7) all subjects had two "normal" ears (as defined by these criteria). Measurements included pure-tone audiometry for 0.25 to 8 kHz, standard 226 Hz tympanometry, ECR for 0.2 to 6 kHz at 60 dB SPL using the Mimosa Acoustics HearID system, and umbo velocity (VU) for 0.3 to 6 kHz at 70 to 90 dB SPL using the HLV-1000 laser Doppler vibrometer (Polytec Inc).

resultsMean power reflectance (|ECR|) was near 1.0 at 0.2 to 0.3 kHz, decreased to a broad minimum of 0.3 to 0.4 between 1 and 4 kHz, and then sharply increased to almost 0.8 by 6 kHz. The mean pressure reflectance phase angle (∠ECR) plotted on a linear frequency scale showed a group delay of approximately 0.1 msec for 0.2 to 6 kHz. Small significant differences were observed in |ECR| at the lowest frequencies between right and left ears and between males and females at 4 kHz. |ECR| decreased with age but reached significance only at 1 kHz. Our ECR measurements were generally similar to previous published reports. Highly significant negative correlations were found between |ECR| and VU for frequencies below 1 kHz. Significant correlations were also found between the tympanometrically determined peak total compliance and |ECR| and VU at frequencies below 1 kHz. The results suggest that middle ear compliance contributes significantly to the measured power reflectance and umbo velocity at frequencies below 1 kHz but not at higher frequencies.

conclusionsThis study has established a database of objective measurements of middle ear function (ECR, umbo velocity, tympanometry) in a population of strictly defined normal-hearing ears. These data will promote our understanding of normal middle ear function and will serve as a control for comparison to similar measurements made in pathological ears.

Indexed as

Acoustic Impedance TestsAdultAudiometry, Pure-ToneCalibrationEar CanalEar, MiddleFemaleHearingHumansMaleMiddle AgedReference ValuesSex CharacteristicsYoung Adult

Identifiers

PMID21857517
PMCPMC3223546
OpenAlexW2040433547

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.