Evidence map›Paper›PMID 21855408›Full record

Trial reportSleep medicine2011

Effectiveness of evening phototherapy for insomnia is reduced by bright daytime light exposure.

Jamie M Zeitzer, Leah Friedman, Jerome A Yesavage

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Sleep medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Real life trumps laboratory in matters of public health.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  14. Nocturia reported in nightly sleep diaries: common occurrence with significant implications?Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2014
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jamie M ZeitzerDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, United States. jzeitzer@stanford.edu
Leah Friedman
Jerome A Yesavage
Stanford University · USVA Palo Alto Health Care System · US

Funding

XOLAIR IN SUBJECTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS WITH FOOD ALLERGYM01RR000070 · NCRR · STANFORD UNIVERSITY · PI PARSONNET, JULIE · 1985 to 2008
$32.4M
TREATMENTS FOR INSOMNIAR01AG012914 · NIA · STANFORD UNIVERSITY · PI YESAVAGE, JEROME A · 1994 to 2003
$1.8M
NCRR NIH HHS M01 RR000070NCRR NIH HHS M01 RR-00070NIA NIH HHS R01 AG012914NIA NIH HHS R01 AG 12914
6 · The paper itself

Abstract

objectiveTo examine the effect of ambulatory daytime light exposure on phase delays and on the advances produced by timed exposure to bright evening or morning light.

methodsAs a subset of a larger study, 32 older (63.0 ± 6.43 years) adults with primary insomnia were randomized to an at-home, single-blind, 12-week, parallel-group study entailing daily exposure to 45 min of scheduled evening or morning bright (∼4000 lux) light. Light exposure patterns during the baseline and the last week of treatment were monitored using actigraphs with built-in illuminance detectors. Circadian phase was determined through analysis of in-laboratory collected plasma melatonin.

resultsLess daytime light exposure during the last week of treatment was significantly associated with larger phase delays in response to evening light (r's>0.78). Less daytime light exposure during the last week of treatment was also associated with a significant delay in wake time (r's>-0.75). There were no such relationships between light exposure history and phase advances in response to morning light.

conclusionsGreater light exposure during the daytime may decrease the ability of evening light, but not morning light, exposure to engender meaningful changes of circadian phase.

Indexed as

LightingAgedAgingChronotherapyCircadian RhythmFemaleHumansMaleMiddle AgedPhotoperiodPhototherapySleep Initiation and Maintenance DisordersSunlightTreatment Outcome

Identifiers

PMID21855408
PMCPMC3176957
OpenAlexW2072518257

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.