Evidence map›Paper›PMID 21855242›Full record

Trial reportMagnetic resonance imaging2011

Automatic quantification of muscle volumes in magnetic resonance imaging scans of the lower extremities.

Gerd Brunner, Vijay Nambi, Eric Yang, Anirudh Kumar, Salim S Virani, Panagiotis Kougias, Dipan Shah, Alan Lumsden, Christie M Ballantyne, Joel D Morrisett

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Magnetic resonance imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Muscle mass assessment in renal disease: the role of imaging techniques.Quantitative imaging in medicine and surgery · 2020
    Review
  14. Article
  15. Observational
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gerd BrunnerDivision of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. gbrunner@bcm.edu
Vijay Nambi
Eric Yang
Anirudh Kumar
Salim S Virani
Panagiotis Kougias
Dipan Shah
Alan Lumsden
Christie M Ballantyne
Joel D Morrisett

Funding

Effect of lipid modification on peripheral arterial disease (PAD)R01HL075824 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI BALLANTYNE, CHRISTIE MITCHELL · 2003 to 2007
$4.4M
ATHEROSCLEROSIS AND VASCULAR BIOLOGY TRAINING CENTERT32HL007812 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI BALLANTYNE, CHRISTIE MITCHELL · 1997 to 2012
$3.4M
LESION QUANTIFICATION IN HUMAN CAROTID ATHEROSCLEROSISR01HL063090 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI MORRISETT, JOEL DAVID · 2002 to 2005
$1.3M
NHLBI NIH HHS R01 HL063090NHLBI NIH HHS R01 HL075824NHLBI NIH HHS R01HL075824NHLBI NIH HHS R01HL63090NHLBI NIH HHS T32 HL007812NHLBI NIH HHS T32HL07812
6 · The paper itself

Abstract

Muscle volume measurements are essential for an array of diseases ranging from peripheral arterial disease, muscular dystrophies, neurological conditions to sport injuries and aging. In the clinical setting, muscle volume is not routinely measured due to the lack of standardized ways for its repeatable quantification. In this paper, we present magnetic resonance muscle quantification (MRMQ), a method for the automatic quantification of thigh muscle volume in magnetic resonance imaging (MRI) scans. MRMQ integrates a thigh segmentation and nonuniform image gradient correction step, followed by feature extraction and classification. The classification step leverages prior probabilities, introducing prior knowledge to a maximum a posteriori classifier. MRMQ was validated on 344 slices taken from 60 MRI scans. Experiments for the fully automatic detection of muscle volume in MRI scans demonstrated an averaged accuracy, sensitivity and specificity for leave-one-out cross-validation of 88.3%, 93.6% and 87.2%, respectively.

Indexed as

AlgorithmsAutomationBrainBrain MappingHumansImage Processing, Computer-AssistedLegLipidsMagnetic Resonance ImagingModels, StatisticalMusclesNormal DistributionPattern Recognition, AutomatedReproducibility of ResultsSensitivity and SpecificityThighLipids

Identifiers

PMID21855242
PMCPMC11670142

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.