Evidence map›Paper›PMID 21854969›Full record

ArticleProgress in brain research2011

Modulation of the brain's functional network architecture in the transition from wake to sleep.

Linda J Larson-Prior, Jonathan D Power, Justin L Vincent, Tracy S Nolan, Rebecca S Coalson, John Zempel, Abraham Z Snyder, Bradley L Schlaggar, Marcus E Raichle, Steven E Petersen

Abstract read
In one paragraph

Article in Progress in brain research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Functional brain organization is stable within individuals across years.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Sleep neuroimaging: Review and future directions.Journal of sleep research · 2025
    Review
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Linda J Larson-PriorNeuroimaging Laboratory, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA. lindap@npg.wustl.edu
Jonathan D Power
Justin L Vincent
Tracy S Nolan
Rebecca S Coalson
John Zempel
Abraham Z Snyder
Bradley L Schlaggar
Marcus E Raichle
Steven E Petersen

Funding

TRACER METHODSP50NS006833 · NINDS · WASHINGTON UNIVERSITY · PI POWERS, WILLIAM J · 1985 to 2010
$12.9M
ROLE OF SUBCORTICAL MOTOR SYSTEMS IN NEUROLOGICAL RECOVERY FOLLOWING STROKEP01NS006833 · NINDS · WASHINGTON UNIVERSITY · PI GRUBB, ROBERT L · 1986 to 1993
–
NINDS NIH HHS NS006833NINDS NIH HHS P50 NS006833
6 · The paper itself

Abstract

The transition from quiet wakeful rest to sleep represents a period over which attention to the external environment fades. Neuroimaging methodologies have provided much information on the shift in neural activity patterns in sleep, but the dynamic restructuring of human brain networks in the transitional period from wake to sleep remains poorly understood. Analysis of electrophysiological measures and functional network connectivity of these early transitional states shows subtle shifts in network architecture that are consistent with reduced external attentiveness and increased internal and self-referential processing. Further, descent to sleep is accompanied by the loss of connectivity in anterior and posterior portions of the default-mode network and more locally organized global network architecture. These data clarify the complex and dynamic nature of the transitional period between wake and sleep and suggest the need for more studies investigating the dynamics of these processes.

Indexed as

BrainBrain MappingElectroencephalographyFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNerve NetNeural PathwaysSleepWakefulness

Identifiers

PMID21854969
PMCPMC3811144

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.