ReviewProgress in brain research2011
Electrophysiological correlates of sleep homeostasis in freely behaving rats.
Review in Progress in brain research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
65 citing papers in PubMed, 111 citations in OpenAlex.
- Sleep homeostasis in OSA: a complementary neurophysiological outcome measure.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- A molecular integrator of sleep duration and interruption.bioRxiv : the preprint server for biology · 2026Article
- Wintering Barnacle Geese Exhibit an Increased Behavioural Drive for Sleep After Sleep Deprivation Without a Clear EEG-Based Sleep Rebound.Journal of sleep research · 2026Article
- Cortical firing dynamics during micro-arousals vary with sleep/wake history and micro-arousal duration.Scientific reports · 2026Article
- Vigilance state dissociation induced by 5-MeO-DMT in mice.Communications biology · 2026Article
- Integrative sleep management: from molecular pathways to conventional and herbal treatments.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice.Molecular brain · 2025Article
- Sleep- and sleep deprivation-related changes of vertex auditory evoked potentials during the estrus cycle in female rats.Scientific reports · 2024Article
- Developmental alcohol exposure is exhausting: Sleep and the enduring consequences of alcohol exposure during development.Neuroscience and biobehavioral reviews · 2024Review
- Homeostatic NREM sleep and salience network function in adult mice exposed to ethanol during development.Frontiers in neuroscience · 2023Article
- Frontal grey matter microstructure is associated with sleep slow waves characteristics in late midlife.Sleep · 2022Article
- Functional states shape the spatiotemporal representation of local and cortex-wide neural activity in mouse sensory cortex.Journal of neurophysiology · 2022Article
- Translational approaches to influence sleep and arousal.Brain research bulletin · 2022Review
- Overnight Delta Dynamics Associated with Daytime Psychomotor Performance in Adults with Insomnia and Healthy Controls.Nature and science of sleep · 2022Article
- Cortico-Hippocampal Oscillations Are Associated With the Developmental Onset of Hippocampal-Dependent Memory.Frontiers in neuroscience · 2022Article
- Sleeping at the switch.eLife · 2021Article
- Homeostatic sleep regulation in the absence of the circadian sleep-regulating component: effect of short light-dark cycles on sleep-wake stages and slow waves.BMC neuroscience · 2021Article
- Extended Visual Sequence Learning Leaves a Local Trace in the Spontaneous EEG.Frontiers in neuroscience · 2021Article
- Do Mosquitoes Sleep?Trends in parasitology · 2020Review
- Sleep Network Deterioration as a Function of Dim-Light-At-Night Exposure Duration in a Mouse Model.Clocks & sleep · 2020Article
5 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The electrical activity of the brain does not only reflect the current level of arousal, ongoing behavior, or involvement in a specific task but is also influenced by what kind of activity, and how much sleep and waking occurred before. The best marker of sleep-wake history is the electroencephalogram (EEG) spectral power in slow frequencies (slow-wave activity, 0.5-4 Hz, SWA) during sleep, which is high after extended wakefulness and low after consolidated sleep. While sleep homeostasis has been well characterized in various species and experimental paradigms, the specific mechanisms underlying homeostatic changes in brain activity or their functional significance remain poorly understood. However, several recent studies in humans, rats, and computer simulations shed light on the cortical mechanisms underlying sleep regulation. First, it was found that the homeostatic changes in SWA can be fully accounted for by the variations in amplitude and slope of EEG slow waves, which are in turn determined by the efficacy of corticocortical connectivity. Specifically, the slopes of sleep slow waves were steeper in early sleep compared to late sleep. Second, the slope of cortical evoked potentials, which is an established marker of synaptic strength, was steeper after waking, and decreased after sleep. Further, cortical long-term potentiation (LTP) was partially occluded if it was induced after a period of waking, but it could again be fully expressed after sleep. Finally, multiunit activity recordings during sleep revealed that cortical neurons fired more synchronously after waking, and less so after a period of consolidated sleep. The decline of all these electrophysiological measures-the slopes of slow waves and evoked potentials and neuronal synchrony-during sleep correlated with the decline of the traditional marker of sleep homeostasis, EEG SWA. Taken together, these data suggest that homeostatic changes in sleep EEG are the result of altered neuronal firing and synchrony, which in turn arise from changes in functional neuronal connectivity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.