ReviewExpert opinion on biological therapy2011
Potential benefits of allogeneic bone marrow mesenchymal stem cells for wound healing.
Review in Expert opinion on biological therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02169362 (Phase I, Double-Blind, Randomized, Controlled Study to Demonstrate the Safety of Applying Autologous Platelet Rich Plasma), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phase I, Double-Blind, Randomized, Controlled Study to Demonstrate the Safety of Applying Autologous Platelet Rich Plasma (PRP) Gel (Magellan® Bio-Bandage™) to Acute Deep Partial Thickness Thermal Injuries
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bone Marrow-Derived Mesenchymal Stem Cell Implants for the Treatment of Focal Chondral Defects of the Knee in Animal Models: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2023Pooled it
- Mesenchymal Stem Cell-Derived Extracellular Vesicles as an Advanced Therapy for Chronic Wounds.Cold Spring Harbor perspectives in biology · 2022Review
- Mesenchymal stem cells are prospective novel off-the-shelf wound management tools.Drug delivery and translational research · 2022Review
- Extracellular Vesicles as Therapeutic Tools for the Treatment of Chronic Wounds.Pharmaceutics · 2021Review
- Mechanism of bone marrow mesenchymal stem cells secreting miR-26a exosomes affecting high glucose-induced skin fibroblasts function by regulating TLR4/NF-κB signaling.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021Article
- Effect of Allogeneic Oral Mucosa Mesenchymal Stromal Cells on Equine Wound Repair.Veterinary medicine international · 2021Article
- Treatment of Full-Thickness Skin Wounds with Blood-Derived CD34Advances in wound care · 2020Article
- Impact of mesenchymal stem cell senescence on inflammaging.BMB reports · 2020Review
- Mesenchymal Stem Cells Application in Wound Tissue Healing in Old Animals.Stem cells and cloning : advances and applications · 2020Article
- Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses.Stem cells translational medicine · 2018Article
- Cellular therapies in trauma and critical care medicine: Looking towards the future.PLoS medicine · 2017Article
- Platelet-derived growth factor and stromal cell-derived factor-1 promote the skin wound repairing effect of bone mesenchymal stem cells: a key role of matrix metalloproteinase 1 and collagens.International journal of clinical and experimental pathology · 2017Article
- Cellular Therapies in Trauma and Critical Care Medicine: Forging New Frontiers.Shock (Augusta, Ga.) · 2015Review
- Mesenchymal Stem Cell Exosomes Induce Proliferation and Migration of Normal and Chronic Wound Fibroblasts, and Enhance Angiogenesis In Vitro.Stem cells and development · 2015Article
- Crosstalk between adrenergic and toll-like receptors in human mesenchymal stem cells and keratinocytes: a recipe for impaired wound healing.Stem cells translational medicine · 2014Article
- Epidermal Differentiation in Barrier Maintenance and Wound Healing.Advances in wound care · 2014Review
- Article
- Quality assessment of tissue specimens for studies of diabetic foot ulcers.Experimental dermatology · 2013Article
- Stimulation of skin and wound fibroblast migration by mesenchymal stem cells derived from normal donors and chronic wound patients.Stem cells translational medicine · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
introductionIt is becoming increasingly evident that select adult stem cells have the capacity to participate in repair and regeneration of damaged and/or diseased tissues. Mesenchymal stem cells have been among the most studied adult stem cells for the treatment of a variety of conditions, including wound healing. AREAS COVERED: Mesenchymal stem cell features potentially beneficial to cutaneous wound healing applications are reviewed. EXPERT OPINION: Given their potential for in vitro expansion and immune modulatory effects, both autologous and allogeneic mesenchymal stem cells appear to be well suited as wound healing therapies. Allogeneic mesenchymal stem cells derived from young healthy donors could have particular advantage over autologous sources where age and systemic disease can be significant factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.