Evidence map›Paper›PMID 21854285›Full record

Trial reportThe American journal of drug and alcohol abuse2011

Design of NIDA CTN Protocol 0047: screening, motivational assessment, referral, and treatment in emergency departments (SMART-ED).

Michael P Bogenschutz, Dennis M Donovan, Bryon Adinoff, Cameron Crandall, Alyssa A Forcehimes, Robert Lindblad, Raul N Mandler, Neal L Oden, Harold I Perl, Robrina Walker

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of drug and alcohol abuse, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  4. The SOS Suicide Prevention Program: Further Evidence of Efficacy and Effectiveness.Prevention science : the official journal of the Society for Prevention Research · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michael P BogenschutzDepartment of Psychiatry, Health Sciences Center, University of New Mexico, Albuquerque, 87131, USA. mbogenschutz@salud.unm.edu
Dennis M Donovan
Bryon Adinoff
Cameron Crandall
Alyssa A Forcehimes
Robert Lindblad
Raul N Mandler
Neal L Oden
Harold I Perl
Robrina Walker

Funding

Project-004UG1DA020024 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI Steven J Shoptaw, MADHUKAR H. TRIVEDI · 2015 to 2026
$71.6M
INSTITUTE FOR TRANSLATIONAL HEALTH SCIENCE (UL1): BPCAUL1RR025014 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$51.5M
CLINICAL TRIALS NETWORK: PACIFIC NORTHWEST NODEU10DA013714 · NIDA · UNIVERSITY OF WASHINGTON · PI DONOVAN, DENNIS MICHAEL, ROLL, JOHN M. · 2001 to 2015
$25.5M
Concept ProjectU10DA020024 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI TRIVEDI, MADHUKAR H. · 2005 to 2015
$22.6M
Clinical Trials Network: Southwest NodeU10DA015833 · NIDA · UNIVERSITY OF NEW MEXICO · PI MCCRADY, BARBARA S · 2002 to 2014
$19.9M
NCRR NIH HHS UL1 RR025014NIDA NIH HHS U10 DA013714NIDA NIH HHS U10DA013714NIDA NIH HHS U10 DA015833NIDA NIH HHS U10DA015833NIDA NIH HHS U10 DA020024NIDA NIH HHS U10DA020024NIDA NIH HHS UG1 DA020024
6 · The paper itself

Abstract

backgroundMedical settings such as emergency departments (EDs) present an opportunity to identify and provide services for individuals with substance use problems who might otherwise never receive any form of assessment, referral, or intervention. Although screening, brief intervention, and referral to treatment models have been extensively studied and are considered effective for individuals with alcohol problems presenting in EDs and other medical settings, the efficacy of such interventions has not been established for drug users presenting in EDs.

objectivesThis article describes the design of a NIDA Clinical Trials Network protocol testing the efficacy of an screening, brief intervention, and referral to treatment model in medical EDs, highlighting considerations that are pertinent to the design of other studies targeting substance use behaviors in medical treatment settings.

methodsThe protocol is described, and critical design decisions are discussed.

resultsDesign challenges included defining treatment conditions, study population, and site characteristics; developing the screening process; choosing the primary outcome; balancing brevity and comprehensiveness of assessment; and selecting the strategy for statistical analysis.

conclusionMany of the issues arising in the design of this study will be relevant to future studies of interventions for addictions in medical settings. SCIENTIFIC SIGNIFICANCE: Optimal trial design is critical to determining how best to integrate substance abuse interventions into medical care.

Indexed as

Research DesignData Interpretation, StatisticalEmergency Service, HospitalHumansMass ScreeningMotivationNational Institute on Drug Abuse (U.S.)Prospective StudiesPsychotherapy, BriefSubstance-Related DisordersUnited States

Identifiers

PMID21854285
PMCPMC3168577

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.