ArticleThe American journal of drug and alcohol abuse2011
Gender research in the National Institute on Drug Abuse National Treatment Clinical Trials Network: a summary of findings.
Article in The American journal of drug and alcohol abuse, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sex- and Gender-Based Analysis in Cannabis Treatment Outcomes: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Psychosocial interventions for pregnant women in outpatient illicit drug treatment programs compared to other interventions.The Cochrane database of systematic reviews · 2015Pooled it
- Gender differences in clinical outcomes for cocaine dependence: randomized clinical trials of behavioral therapy and disulfiram.Drug and alcohol dependence · 2014Trial
- A qualitative study exploring motivations for participating in research among women who use opioids.PloS one · 2025Article
- The representation of females in clinical trials for substance use disorder conducted in the United States (2010-19).Addiction (Abingdon, England) · 2022Review
- Gender-specific correlates of nonmedical use of prescription medications in a diverse primary care sample.Drug and alcohol dependence · 2022Article
- Women's views on barriers and facilitators for seeking alcohol and drug treatment in Belgium.Nordisk alkohol- & narkotikatidskrift : NAT · 2021Article
- The impact of poly-traumatization on treatment outcomes in young people with substance use disorders.BMC psychiatry · 2021Article
- Sex-specific risk profiles for substance use among college students.Brain and behavior · 2021Article
- Opioid Use Disorder in Women and the Implications for Treatment.Psychiatric research and clinical practice · 2021Article
- Research on women with substance use disorders: Reviewing progress and developing a research and implementation roadmap.Drug and alcohol dependence · 2019Review
- Sex differences in stress-related alcohol use.Neurobiology of stress · 2019Review
- Impact of Behavioral Drug Abuse Treatment on Sexual Risk Behaviors: An Integrative Data Analysis of Eight Trials Conducted Within the National Drug Abuse Treatment Clinical Trials Network.Prevention science : the official journal of the Society for Prevention Research · 2018Article
- Gender Differences in HIV Sexual Risk Behaviors Among Clients of Substance Use Disorder Treatment Programs in the U.S.Archives of sexual behavior · 2017Article
- Sex-specific linkage scans in opioid dependence.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2017Article
- Gender Differences in Emergency Department Visits and Detox Referrals for Illicit and Nonmedical Use of Opioids.The western journal of emergency medicine · 2016Article
- Gender Considerations in Addiction: Implications for Treatment.Current treatment options in psychiatry · 2015Article
- Effect of the Affordable Care Act's young adult insurance expansions on hospital-based mental health care.The American journal of psychiatry · 2015Article
- A research agenda for gender and substance use disorders in the emergency department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2014Article
- Psychosocial correlates of gender-based violence among HIV-infected and HIV-uninfected women in three US cities.AIDS patient care and STDs · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
backgroundThe National Institute of Drug Abuse's National Drug Abuse Treatment Clinical Trials Network (CTN) was established to foster translation of research into practice in substance abuse treatment settings. The CTN provides a unique opportunity to examine in multi-site, translational clinical trials, the outcomes of treatment interventions targeting vulnerable subgroups of women; the comparative effectiveness of gender-specific protocols to reduce risk behaviors; and gender differences in clinical outcomes.
objectivesTo review gender-related findings from published CTN clinical trials and related studies from January 2000 to March 2010.
methodsCTN studies were selected for review if they focused on treatment outcomes or services for special populations of women with substance use disorders (SUDs) including those with trauma histories, pregnancy, co-occurring eating and other psychiatric disorders, and HIV risk behaviors; or implemented gender-specific protocols. The CTN has randomized 11,500 participants (41% women) across 200 clinics in 24 randomized controlled trials in community settings, of which 4 have been gender-specific.
resultsThis article summarizes gender-related findings from CTN clinical trials and related studies, focusing on trauma histories, pregnancy, co-occurring eating and other psychiatric disorders, and HIV risk behaviors.
conclusionsThese published studies have expanded the evidence base regarding interventions for vulnerable groups of women with SUDs as well as gender-specific interventions to reduce HIV risk behaviors in substance-using men and women. The results also underscore the complexity of accounting for gender in the design of clinical trials and analysis of results. SCIENTIFIC SIGNIFICANCE: To fully understand the relevance of gender-specific moderators and mediators of outcome, it is essential that future translational studies adopt more sophisticated approaches to understanding and measuring gender-relevant factors and plan sample sizes that are adequate to support more nuanced analytic methods.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.