Evidence map›Paper›PMID 21853318›Full record

ArticleIndian journal of pediatrics2012

Neurodevelopmental outcomes of extremely low birth weight infants ventilated with continuous positive airway pressure vs. mechanical ventilation.

Cameron W Thomas, Jareen Meinzen-Derr, Steven B Hoath, Vivek Narendran

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Indian journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cameron W ThomasDepartment of Neurology, MLC 2015, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, USA. Cameron.Thomas@cchmc.org
Jareen Meinzen-Derr
Steven B Hoath
Vivek Narendran
Cincinnati Children's Hospital Medical Center · US

Funding

Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2012 to 2014
$9.9M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD027853 · NICHD · UNIVERSITY OF CINCINNATI · PI SCHIBLER, KURT R · 1991 to 2015
$6.2M
NCATS NIH HHS UL1 TR000077NICHD NIH HHS U10 HD027853
6 · The paper itself

Abstract

objectiveTo compare continuous positive airway pressure (CPAP) vs. traditional mechanical ventilation (MV) at 24 h of age as predictors of neurodevelopmental (ND) outcomes in extremely low birth weight (ELBW) infants at 18-22 months corrected gestational age (CGA).

methodsInfants ≤1000 g birth weight born from January 2000 through December 2006 at two hospitals at the Cincinnati site of the National Institute of Child Health and Human Development Neonatal Research Network were evaluated comparing CPAP (n = 198) vs. MV (n = 109). Primary outcomes included the Bayley Score of Infant Development Version II (BSID-II), presence of deafness, blindness, cerebral palsy, bronchopulmonary dysplasia and death.

resultsVentilatory groups were similar in gender, rates of preterm prolonged rupture of membranes, antepartum hemorrhage, use of antenatal antibiotics, steroids, and tocolytics. Infants receiving CPAP weighed more, were older, were more likely to be non-Caucasian and from a singleton pregnancy. Infants receiving CPAP had better BSID-II scores, and lower rates of BPD and death.

conclusionsAfter adjusting for acuity differences, ventilatory strategy at 24 h of age independently predicts long-term neurodevelopmental outcome in ELBW infants.

Indexed as

Infant, Extremely Low Birth WeightRespiration, ArtificialContinuous Positive Airway PressureDevelopmental DisabilitiesFemaleHumansInfant, NewbornMaleNervous System DiseasesRetrospective Studies

Identifiers

PMID21853318
PMCPMC3498084
OpenAlexW1963569475

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.