ArticlePsychiatry investigation2011
Do defense styles of ego relate to volumes of orbito-frontal cortex in patients with obsessive-compulsive disorder?
Article in Psychiatry investigation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Metacognition and Its Relationship With Orbitofrontal Cortex and Thalamus Volumes in Patients With Obsessive-Compulsive Disorder.Brain and behavior · 2025Article
- Metacognitive Therapy in Patients with Obsessive-Compulsive Disorder: A review.Alpha psychiatry · 2022Review
- Heavy Study Investment: An Analysis of the Defense Mechanisms Characterizing Studyholism and Study Engagement.International journal of environmental research and public health · 2022Article
- Decreased Nucleus Accumbens Connectivity at Rest in Medication-Free Patients with Obsessive-Compulsive Disorder.Neural plasticity · 2021Article
- Abnormalities of white matter microstructure in unmedicated patients with obsessive-compulsive disorder: Changes after cognitive behavioral therapy.Brain and behavior · 2019Article
- Abnormal corticostriatal-limbic functional connectivity in obsessive-compulsive disorder during reward processing and resting-state.NeuroImage. Clinical · 2013Article
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Authors and funding
6 authors.
Funding
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Abstract
objectiveAlthough the importance of orbito-frontal cortex (OFC) is established in the pathogenesis of obsessive compulsive disorder (OCD), no study have evaluated its relation to the traditional psychodynamic perspective. In the present study, we aimed to evaluate the relationship between the defense styles consisting of mature, immature and neurotic defenses and OFC volumes of patients with OCD.
methodsSubjects were selected among those of our previous study, and so eighteen patients with OCD and same number of healthy controls were took into the study. The patients and controls had underwent magnetic resonance imaging (MRI). In addition, the Defense Style Questionnaire-40 was administered to obtain defense styles of patients and controls.
resultsNo significant relationship was found between the right OFC volumes of both the patient and control groups and their scores of mature, neurotic, or immature defense mechanisms. As for the left OFC volumes, the only significant relationship for the scores of immature defense mechanism was found in the patient group.
conclusionThe results of the present study indicated that there was no significant relationship between OFC volumes of the patient group and their scores of mature, neurotic, or immature defense mechanisms, except a significant relation with the scores of immature defense mechanisms.
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