ArticleNature immunology2011
IL-17R signaling: new players get in on the Act1.
Article in Nature immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- AI-validated fusion proteins for local inhibition of interleukin-17A.Journal of controlled release : official journal of the Controlled Release Society · 2026Article
- The cytokine CSBF inhibits the IL-17A and TNF-α inflammatory pathways via SUSD2-ACT1 in keratinocytes and alleviates IMQ-induced psoriasis.Cellular & molecular immunology · 2025Article
- Roles of IL-25 in Type 2 Inflammation and Autoimmune Pathogenesis.Frontiers in immunology · 2021Review
- Interleukin-17A negatively regulates lymphangiogenesis in T helper 17 cell-mediated inflammation.Mucosal immunology · 2018Article
- Protein Kinase Serine/Threonine Kinase 24 Positively Regulates Interleukin 17-Induced Inflammation by Promoting IKK Complex Activation.Frontiers in immunology · 2018Article
- Neutrophils negatively regulate induction of mucosal IgA responses after sublingual immunization.Mucosal immunology · 2015Article
- A pharmacogenetics study in Mozambican patients treated with nevirapine: full resequencing of TRAF3IP2 gene shows a novel association with SJS/TEN susceptibility.International journal of molecular sciences · 2015Article
- TRAF3IP2 gene and systemic lupus erythematosus: association with disease susceptibility and pericarditis development.Immunogenetics · 2013Article
- Negative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25.Nature immunology · 2012Article
- New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis.Arthritis research & therapy · 2012Review
Corrections and comments
- Comment on
- Comment on
Authors and funding
1 author.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
21852777What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.