ArticleJournal of perinatology : official journal of the California Perinatal Association2012
Consanguinity, prematurity, birth weight and pregnancy loss: a prospective cohort study at four primary health center areas of Karnataka, India.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- The spectrum of chromosomal translocations in the Arab world: ethnic-specific chromosomal translocations and their relevance to diseases.Chromosoma · 2022Pooled it
- Factors associated with stillbirth in selected countries of South Asia: A systematic review of observational studies.PloS one · 2020Pooled it
- Maternal Anthropometric and Obstetric Risk Factors for Small-for-Gestational-Age Births in Anuradhapura District, Sri Lanka: A Retrospective Case-Control Study.Annals of global health · 2026Article
- Consanguinity and adverse fetal outcomes- a population-based cohort study from a multiethnic population in the Middle East.BMC pregnancy and childbirth · 2025Article
- Linkages between consanguinity, pregnancy outcomes and offspring mortality in twenty-first century India.Scientific reports · 2024Article
- Assessment of Perceptions and Predictors Towards Consanguinity: A Cross-Sectional Study from Palestine.Journal of multidisciplinary healthcare · 2023Article
- Association between adverse pregnancy outcomes and preceding risk factors: a cross-sectional study from Nashik District, India.BMC pregnancy and childbirth · 2021Article
- Stillbirth 2010-2018: a prospective, population-based, multi-country study from the Global Network.Reproductive health · 2020Article
- Global Network for Women's and Children's Health Research: probable causes of stillbirth in low- and middle-income countries using a prospectively defined classification system.BJOG : an international journal of obstetrics and gynaecology · 2018Observational
- [Fetal autopsies : Relic or still a gold standard?]Der Pathologe · 2017Article
- The Global Network Neonatal Cause of Death algorithm for low-resource settings.Acta paediatrica (Oslo, Norway : 1992) · 2017Article
- Structural and genomic variation in preterm birth.Pediatric research · 2016Article
- UK Pakistani views on the adverse health risks associated with consanguineous marriages.Journal of community genetics · 2015Article
- Etiology and clinical profile of childhood optic nerve atrophy at a tertiary eye care center in South India.Indian journal of ophthalmology · 2015Article
- Re: perinatal mortality rate as a quality indicator of healthcare in Al-dakhiliyah region, oman.Sultan Qaboos University medical journal · 2014Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
Abstract
objectiveTo determine whether consanguinity adversely influences pregnancy outcome in South India, where consanguinity is a common means of family property retention. STUDY
designData were collected from a prospective cohort of 647 consenting women, consecutively registered for antenatal care between 14 and 18 weeks gestation, in Belgaum district, Karnataka in 2005. Three-generation pedigree charts were drawn for consanguineous participants. χ (2)-Test and Student's t-test were used to assess categorical and continuous data, respectively, using SPSS version 14. Multivariate logistic regression adjusted for confounding variables.
resultOverall, 24.1% of 601 women with singleton births and outcome data were consanguineous. Demographic characteristics between study groups were similar. Non-consanguineous couples had fewer stillbirths (2.6 vs 6.9% P=0.017; adjusted P=0.050), miscarriages (1.8 vs 4.1%, P=0.097; adjusted P=0.052) and lower incidence of birth weight <2500 g (21.8 vs 29.5%, P=0.071, adjusted P=0.044). Gestation <37 weeks was 6.2% in both the groups. Adjusted for consanguinity and other potential confounders, age <20 years was protective of stillbirth (P=0.01), pregnancy loss (P=0.023) and preterm birth (P=0.013), whereas smoking (P=0.015) and poverty (P=0.003) were associated with higher rates of low birth weight.
conclusionConsanguinity significantly increases pregnancy loss and birth weight <2500 g.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.