Evidence map›Paper›PMID 21852723›Full record

ArticlePhysics in medicine and biology2011

Characterization of a high-purity germanium detector for small-animal SPECT.

Lindsay C Johnson, Desmond L Campbell, Ethan L Hull, Todd E Peterson

Abstract readEvaluation Study
In one paragraph

Article in Physics in medicine and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Development of a Germanium Small-Animal SPECT System.IEEE transactions on nuclear science · 2015
    Article
  5. Article
  6. Advances in preclinical SPECT instrumentation.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lindsay C JohnsonInstitute of Imaging Science, Vanderbilt University, Nashville, TN, USA.
Desmond L Campbell
Ethan L Hull
Todd E Peterson
Vanderbilt University · US

Funding

Training in Cellular and Molecular Imaging of CancerR25CA136440 · NCI · VANDERBILT UNIVERSITY · PI GORE, JOHN C · 2009 to 2013
$2.1M
Germanium Gamma CamerasR44RR031937 · NCRR · PHDS COMPANY · PI HULL, ETHAN · 2011 to 2011
$150k
NCI NIH HHS R25 CA136440NCI NIH HHS R25CA136440NCRR NIH HHS R44 RR031937NCRR NIH HHS R44RR031937
6 · The paper itself

Abstract

We present an initial evaluation of a mechanically cooled, high-purity germanium double-sided strip detector as a potential gamma camera for small-animal SPECT. It is 90 mm in diameter and 10 mm thick with two sets of 16 orthogonal strips that have a 4.5 mm width with a 5 mm pitch. We found an energy resolution of 0.96% at 140 keV, an intrinsic efficiency of 43.3% at 122 keV and a FWHM spatial resolution of approximately 1.5 mm. We demonstrated depth-of-interaction estimation capability through comparison of pinhole acquisitions with a point source on and off axes. Finally, a flood-corrected flood image exhibited a strip-level uniformity of less than 1%. This high-purity germanium offers many desirable properties for small-animal SPECT.

Indexed as

GermaniumModels, AnimalAnimalsElectromagnetic FieldsEquipment DesignGamma CamerasImage EnhancementParticle AcceleratorsPhantoms, ImagingReproducibility of ResultsSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonGermanium

Identifiers

PMID21852723
PMCPMC3178965
OpenAlexW2075985622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.