Evidence map›Paper›PMID 21852639›Full record

ArticleAmerican journal of public health2012

Secondhand tobacco smoke: a source of lead exposure in US children and adolescents.

Andria Apostolou, Esther Garcia-Esquinas, Jeffrey J Fadrowski, Pat McLain, Virginia M Weaver, Ana Navas-Acien

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05016505 (A Randomized Controlled Trial to Support Smoke-Free Policy Compliance in Public Housing), which is not on this map. Cited by 52 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05016505 nacompletednot on this mapstarted 2022, after this paper: background citation

A Randomized Controlled Trial to Support Smoke-Free Policy Compliance in Public Housing

TypeinterventionalSponsorColumbia UniversityRan2022 to 2025Enrolled405ConditionsSmoking, Smoking Cessation, Smoking Reduction, Smoking BehaviorsArmsReduction (relocation and reduction of personal smoking) and cessation, Resident Endorsement
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 105 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andria ApostolouDepartment of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Esther Garcia-Esquinas
Jeffrey J Fadrowski
Pat McLain
Virginia M Weaver
Ana Navas-Acien
Johns Hopkins University · US

Funding

Race/Ethnicity, Menthol Cigarettes, and Biomarkers of Tobacco Use in the U.S.R03CA153959 · NCI · JOHNS HOPKINS UNIVERSITY · PI NAVAS-ACIEN, ANA · 2010 to 2011
$156k
NCI NIH HHS R03 CA153959NCI NIH HHS R03CA153959
6 · The paper itself

Abstract

objectivesWe evaluated the relationship between secondhand tobacco smoke (SHS) exposure and blood lead levels in US children and adolescents.

methodsWe analyzed data from 6830 participants aged 3-19 years in the National Health and Nutrition Examination Survey (1999-2004) who were not active smokers and for whom SHS exposure information and blood lead measurements were available.

resultsAfter multivariable adjustment, participants in the highest quartile of serum cotinine (≥ 0.44 μg/L) had 28% (95% confidence interval = 21%, 36%) higher blood lead levels than had those in the lowest quartile (< 0.03 μg/L). Similarly, blood lead levels were 14% and 24% higher in children who lived with 1 or with 2 or more smokers, respectively, than they were in children living with no smokers. Among participants for whom lead dust information was available, the associations between SHS and blood lead levels were similar before and after adjustment for lead dust concentrations.

conclusionsSHS may contribute to increased blood lead levels in US children. Lead dust does not appear to mediate this association, suggesting inhalation as a major pathway of exposure. Eliminating SHS exposure could reduce lead exposure in children.

Indexed as

AdolescentChildChild, PreschoolCotinineCross-Sectional StudiesDemographyEnvironmental ExposureFemaleHousingHumansInhalation ExposureLeadMaleNutrition SurveysResidence CharacteristicsSocial ClassCotinineLeadTobacco Smoke Pollution

Identifiers

PMID21852639
PMCPMC3489360
OpenAlexW2100944043

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.