Evidence map›Paper›PMID 21852368›Full record

ArticleAJNR. American journal of neuroradiology2011

Optimal presentation modes for detecting brain tumor progression.

B J Erickson, C P Wood, T J Kaufmann, J W Patriarche, J Mandrekar

Abstract readValidation Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Utility of image fusion software in identifying shunt malfunction.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Article
  3. Article
  4. Consensus recommendations on standardized magnetic resonance imaging protocols for multicenter canine brain tumor clinical trials.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2018
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

B J EricksonDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA. bje@mayo.edu
C P Wood
T J Kaufmann
J W Patriarche
J Mandrekar

Funding

Change Detection in Serial MRIs of Patients with Brain GliomasR21CA121539 · NCI · MAYO CLINIC ROCHESTER · PI ERICKSON, BRADLEY J. · 2007 to 2008
$266k
NCI NIH HHS R21 CA121539NCI NIH HHS R21CA121539
6 · The paper itself

Abstract

background and purposeA common task in radiology interpretation is visual comparison of images. The purpose of this study was to compare traditional side-by-side and in-place (flicker) image presentation modes with advanced methods for detecting primary brain tumors on MR imaging. MATERIALS AND

methodsWe identified 66 patients with gliomas and 3 consecutive brain MR imaging examinations (a "triplet"). A display application that presented images in side-by-side mode with or without flicker display as well as display of image subtraction or automated change detection information (also with and without flicker display) was used by 3 board-certified neuroradiologists. They identified regions of brain tumor progression by using this display application. Each case was reviewed using all modes (side-by-side presentation with and without flicker, subtraction with and without flicker, and change detection with and without flicker), with results compared via a panel rating.

resultsAutomated change detection with or without flicker (P < .0027) as well as subtraction with or without flicker (P < .0027) were more sensitive to tumor progression than side-by-side presentation in cases where all 3 raters agreed. Change detection afforded the highest interrater agreement, followed by subtraction. Clinically determined time to progression was longer for cases rated as nonprogressing by using subtraction images and change-detection images both with and without flicker display mode compared with side-by-side presentation.

conclusionsAutomated change detection and image subtraction, with and without flicker display mode, are superior to side-by-side image comparison.

Indexed as

AgedAlgorithmsBrain NeoplasmsDisease ProgressionFemaleGliomaHumansMagnetic Resonance ImagingMaleMiddle AgedObserver VariationReference StandardsReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID21852368
PMCPMC3909498

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.