Evidence map›Paper›PMID 21852281›Full record

Trial reportAmerican journal of Alzheimer's disease and other dementias2011

Six-month walking program changes cognitive and ADL performance in patients with Alzheimer.

Massimo Venturelli, Renato Scarsini, Federico Schena

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of Alzheimer's disease and other dementias, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 111 papers, 31 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 31 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02462291 nacompletednot on this mapstarted 2015, after this paper: background citation

Effectiveness of Environmental Therapy in Patients With Alzheimer's Disease

TypeinterventionalSponsorUniversita di VeronaRan2015 to 2015Enrolled163ConditionsAlzheimer Disease, Behavioral Disorders, Cognitive ImpairmentArmsEcological Environmental therapy
NCT03034746 nacompletednot on this mapstarted 2013, after this paper: background citation

Impact of Physical Activity on Successful Aging: Multidisciplinary Analysis of Mechanisms and Outcomes

TypeinterventionalSponsorUniversita di VeronaRan2013 to 2016Enrolled90ConditionsAlzheimer Disease, Cognitive Impairment, Physical ActivityArmsPhysical activity (PA), cognitive treatment (CT)
3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 31 syntheses or guidelines pooled it.

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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Massimo VenturelliDepartment of Neurological, Morphological and Motor Sciences, University of Verona, Italy. massimo.venturelli@univr.it
Renato Scarsini
Federico Schena

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motor inactivity is typical in the later stages of Alzheimer's disease although there is evidence that physical exercise can reduce depression and enhance performance of daily activities. The aim of this study was to determine whether a walking program could reduce the functional and cognitive decline of elderly nursing home residents in the later stages of Alzheimer's disease. A total of 21 patients (84 ± 5 years) were randomly assigned to a walking program (WG) or to a control group (CG). A 6-minute walking test (6WT), the Barthel index of activities of daily living (ADLs), and Mini-Mental State Examination (MMSE) tests were performed before and after 24 weeks of the program. The WG showed significant improvement in the 6WT (20%) and ADLs (23%), while the CG decreased in MMSE (-47%), the WG had a slower decline (-13%). This study indicates that it is possible to stabilize the progressive cognitive dysfunctions in nursing home residents with Alzheimer's disease through a specific walking program.

Indexed as

Exercise TherapyActivities of Daily LivingAged, 80 and overAlzheimer DiseaseBlood GlucoseBlood PressureCognitionFemaleHumansMaleNeuropsychological TestsPatient ComplianceWalkingBlood Glucose

Identifiers

PMID21852281
PMCPMC10845333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.