Evidence map›Paper›PMID 21851933›Full record

ArticleComputers in biology and medicine2011

Anatomic and electro-physiologic connectivity of the language system: a combined DTI-CCEP study.

Christopher R Conner, Timothy M Ellmore, Michael A DiSano, Thomas A Pieters, Andrew W Potter, Nitin Tandon

Abstract read
In one paragraph

Article in Computers in biology and medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Article
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  6. Beyond Broca and Wernicke: Epilepsy surgery in the language areas.Epileptic disorders : international epilepsy journal with videotape · 2026
    Review
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  18. Thalamo-cortical evoked potentials during stimulation of the dentato-rubro-thalamic tract demonstrate synaptic filtering.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher R ConnerVivian L. Smith Department of Neurosurgery, University of Texas Medical School at Houston, USA.
Timothy M Ellmore
Michael A DiSano
Thomas A Pieters
Andrew W Potter
Nitin Tandon

Funding

U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
NCRR NIH HHS KL2 RR0224149NCRR NIH HHS UL1 RR024148
6 · The paper itself

Abstract

Here we present a novel multimodal analysis of network connectivity in the language system. We assessed connectivity of Broca's area using tractography with diffusion tensor imaging (DTI), and with cortico-cortical evoked potentials (CCEPs) to measure the spread of artificial currents applied directly to human cortex. We found that both the amplitude and latency of CCEP currents significantly correlates (r(2)=0.41, p<10(-16)) with the number of DTI pathways connecting the stimulation and recording loci. This strategy of relating electrical information flow with the neural architecture will likely yield new insights into cognitive processes.

Indexed as

LanguageAdultDiffusion Tensor ImagingElectrodes, ImplantedEpilepsyEvoked PotentialsFemaleFrontal LobeHumansMaleMiddle AgedNerve NetRegression Analysis

Identifiers

PMID21851933
PMCPMC3223284

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.