Evidence map›Paper›PMID 21850606›Full record

ArticleDysphagia2012

Does PEG use cause dysphagia in head and neck cancer patients?

Susan Langmore, Gintas P Krisciunas, Keri Vasquez Miloro, Steven R Evans, Debbie M Cheng

Open access · greenAbstract read
In one paragraph

Article in Dysphagia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
19.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 134 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Prospective clinical study on long-term swallowing function and voice quality in advanced head and neck cancer patients treated with concurrent chemoradiotherapy and preventive swallowing exercises.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2015
    Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Insomnia associated with patient-reported outcomes in head and neck cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Dysphagia Advances in Head and Neck Cancer.Current otorhinolaryngology reports · 2023
    Review
  16. Article
  17. The natural history of weight and swallowing outcomes in oropharyngeal cancer patients following radiation or concurrent chemoradiation therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  18. Article
  19. Article
  20. Early oral feeding following esophagectomy.Journal of thoracic disease · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Susan LangmoreOtolaryngology Department, Boston University Medical Center, 820 Harrison Ave., Boston, MA 02118, USA. langmore@bu.edu
Gintas P Krisciunas
Keri Vasquez Miloro
Steven R Evans
Debbie M Cheng
Boston University · USBoston Medical Center · US

Funding

Efficacy of Electrical Stimulation for Dysphagia in Head & Neck Cancer PatientsR01CA120950 · NCI · BOSTON MEDICAL CENTER · PI LANGMORE, SUSAN E · 2007 to 2011
$2.6M
NCI NIH HHS R01 CA120950NCI NIH HHS R01CA120950-03
6 · The paper itself

Abstract

Percutaneous endoscopic gastrostomy (PEG) use is common in patients who undergo radiotherapy (RT) for head and neck cancer to maintain weight and nutrition during treatment. However, the true effect of PEG use on weight maintenance and its potential impact on long-term dysphagia outcomes have not been adequately studied. This retrospective study looked at swallowing-related outcomes among patients who received prophylactic PEG vs. those who did not, and among patients who maintained oral diets vs. partial oral diets vs. those who were nil per os (NPO). Outcomes were assessed at the end of RT and at 3, 6, and 12 months post RT. A comprehensive review of patients' medical charts for a 6-year period yielded 59 subjects with complete data. Results showed no difference in long-term percent weight change between the prophylactic PEG patients vs. all others, or between patients who, during RT, had oral diets vs. partial oral diets vs. NPO. However, those who did not receive prophylactic PEGs and those who maintained an oral or a partial oral diet during RT had significantly better diet outcomes at all times post RT. Dependence on a PEG may lead to adverse swallowing ability in post-irradiated head and neck cancer patients possibly due to decreased use of the swallowing musculature.

Indexed as

AdultAgedAged, 80 and overBody WeightDeglutition DisordersDietEnteral NutritionFemaleGastrostomyHead and Neck NeoplasmsHumansMaleMiddle AgedTime Factors

Identifiers

PMID21850606
PMCPMC4521592
OpenAlexW2118829544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.