Trial reportJournal of behavioral medicine2012
Choice and placebo expectation effects in the context of pain analgesia.
Trial report in Journal of behavioral medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- To Ask or Not to Ask: Does Inquiring About Participants' Expectations Influence the Placebo Effect? A Placebo Mechanism Study in Healthy Volunteers.European journal of pain (London, England) · 2026Trial
- Harnessing the placebo effect to enhance emotion regulation effectiveness and choice.Scientific reports · 2023Trial
- Enhancing the placebo response: functional magnetic resonance imaging evidence of memory and semantic processing in placebo analgesia.The journal of pain · 2014Trial
- Predictors of users' adherence to a fully automated digital intervention to manage insomnia complaints.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Socially Acquired Nocebo Effects Generalize but Are Not Attenuated by Choice.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Article
- Microdosing with psychedelics to self-medicate for ADHD symptoms in adults: A prospective naturalistic study.Neuroscience applied · 2022Article
- Placebos as a Source of Agency: Evidence and Implications.Frontiers in psychiatry · 2019Review
- Estimation of treatment preference effects in clinical trials when some participants are indifferent to treatment choice.BMC medical research methodology · 2017Article
- Identifying when choice helps: clarifying the relationships between choice making, self-construal, and pain.Journal of behavioral medicine · 2016Article
- Aligning research and practice: implications of patient-centered care for placebo effects.The patient · 2014Article
- Can an educational handout enhance placebo analgesia for experimentally-induced pain?PloS one · 2013Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current experiment examined whether having choice over treatment options facilitates or inhibits the strength of placebo expectations in the context of pain perception. All participants were exposed to an aversive stimulus (i.e., the cold pressor task), and participants in some conditions were given expectations for two pain-relieving treatments (actually the same inert ointment mixture). Critically, participants in these expectation conditions were also given a choice or not about which of the two treatments they preferred to use. Participants in a control condition were not provided with a treatment expectation. Despite receiving the same inert treatment, participants who had a choice over treatments showed increased placebo analgesia as compared to participants not given a choice and participants in the control condition. Moreover, this effect was mediated by changes in anxiety. Explanations and implications for these results are discussed.
Indexed as
Identifiers
21850515What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.