GuidelinePediatric radiology2012
Guidelines for imaging retinoblastoma: imaging principles and MRI standardization.
Guideline in Pediatric radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06367569 (Multicenter Evaluation of Baseline MRI Screening With Extended Follow-up of Pineal Cysts for Early Detection of Pineoblastoma in Children With Retinoblastoma), which is not on this map. Cited by 85 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multicenter Evaluation of Baseline MRI Screening With Extended Follow-up of Pineal Cysts for Early Detection of Pineoblastoma in Children With Retinoblastoma
Who cites it
85 citing papers in PubMed, 3 syntheses or guidelines pooled it, 224 citations in OpenAlex.
- Practical guidelines on imaging of retinoblastoma: a 2025 update on behalf of the European Retinoblastoma Imaging Collaboration and the European Retinoblastoma Group.European radiology · 2026Guideline
- Diagnostic performance of MRI of post-laminar optic nerve invasion detection in retinoblastoma: A systematic review and meta-analysis.Neuroradiology · 2021Pooled it
- The essence of the Japan Radiological Society/Japanese College of Radiology Imaging Guideline.Japanese journal of radiology · 2016Guideline
- Nanoprobe-Enabled Precision Imaging and Panoramic Boundary Delineation in Retinoblastoma.Cancer innovation · 2026Review
- Gold Nanoparticles in Retinoblastoma: A Promising Approach for Diagnosis and Treatment.Ocular oncology and pathology · 2026Review
- Quantitative assessment of perfusion-weighted magnetic resonance imaging for the differential diagnosis of various intraocular lesions.Neuroradiology · 2026Article
- Enhanced prediction of postlaminar optic nerve invasion in retinoblastoma using high-resolution MRI: integrating qualitative imaging features, optic nerve measurements and tumor radiomics.European radiology · 2026Article
- A Rare and Delayed Presentation of Retinoblastoma in an 8-Year-Old Child: A Case Report.Clinical optometry · 2026Article
- A-eye: Automated 3D MRI segmentation and morphometric feature extraction for eye and orbit atlas construction.PloS one · 2026Article
- Magnetic resonance features in advanced retinoblastoma - what a paediatric radiologist needs to know.Pediatric radiology · 2025Review
- Retinocytoma: understanding pathogenesis, diagnosis, and treatment approaches.International journal of retina and vitreous · 2025Review
- Retinoblastoma and beyond: pediatric orbital mass lesions.Neuroradiology · 2025Review
- Epidemiology, Diagnosis and Genetics of Retinoblastoma: ICMR Consensus Guidelines.Indian journal of pediatrics · 2024Review
- Differentiating MYCN-amplified RB1 wild-type retinoblastoma from biallelic RB1 mutant retinoblastoma using MR-based radiomics: a retrospective multicenter case-control study.Scientific reports · 2024Article
- Optic nerve thickening on high-spatial-resolution MRI predicts early-stage postlaminar optic nerve invasion in retinoblastoma.European radiology · 2024Article
- Geometrical accuracy of magnetic resonance imaging for ocular proton therapy planning.Physics and imaging in radiation oncology · 2024Article
- Pediatric orbital lesions: ocular pathologies.Pediatric radiology · 2024Article
- Comparison of HASTE versus EPI-Based DWI for Retinoblastoma and Correlation with Prognostic Histopathologic Parameters.AJNR. American journal of neuroradiology · 2024Article
- Congenital Malformations of the Eye: A Pictorial Review and Clinico-Radiological Correlations.Journal of ophthalmology · 2024Review
- Panretinal Optical Coherence Tomography.IEEE transactions on medical imaging · 2023Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Retinoblastoma is the most common intraocular tumor in children. The diagnosis is usually established by the ophthalmologist on the basis of fundoscopy and US. Together with US, high-resolution MRI has emerged as an important imaging modality for pretreatment assessment, i.e. for diagnostic confirmation, detection of local tumor extent, detection of associated developmental malformation of the brain and detection of associated intracranial primitive neuroectodermal tumor (trilateral retinoblastoma). Minimum requirements for pretreatment diagnostic evaluation of retinoblastoma or mimicking lesions are presented, based on consensus among members of the European Retinoblastoma Imaging Collaboration (ERIC). The most appropriate techniques for imaging in a child with leukocoria are reviewed. CT is no longer recommended. Implementation of a standardized MRI protocol for retinoblastoma in clinical practice may benefit children worldwide, especially those with hereditary retinoblastoma, since a decreased use of CT reduces the exposure to ionizing radiation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.