Evidence map›Paper›PMID 21849030›Full record

ArticleBMC musculoskeletal disorders2011

Anamnestic risk factor questionnaire as reliable diagnostic instrument for osteoporosis (reduced bone morphogenic density).

Leila Kolios, Caner Takur, Arash Moghaddam, Mirjam Hitzler, Heinrich Schmidt-Gayk, Arnold J Suda, Bernd Höner, Paul A Grützner, Christoph Wölfl

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Leila KoliosDepartment for Plastic-, Reconstructive and Handsurgery, Burn Care Centre, BG Unfallklinik Ludwigshafen, Ludwig-Guttmann-Str,13, 67071 Ludwigshafen, Germany. leilakolios@freenet.de
Caner Takur
Arash Moghaddam
Mirjam Hitzler
Heinrich Schmidt-Gayk
Arnold J Suda
Bernd Höner
Paul A Grützner
Christoph Wölfl
Klinikum Ludwigshafen · DEBerufsgenossenschaftliche Unfallklinik Ludwigshafen · DESRH Hochschule Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporosis is a major health problem worldwide, and is included in the WHO list of the top 10 major diseases. However, it is often undiagnosed until the first fracture occurs, due to inadequate patient education and lack of insurance coverage for screening tests. Anamnestic risk factors like positive family anamnesis or early menopause are assumed to correlate with reduced BMD.

methodsIn our study of 78 patients with metaphyseal long bone fractures, we searched for a correlation between anamnestic risk factors, bone specific laboratory values, and the bone morphogenic density (BMD). Each indicator was examined as a possible diagnostic instrument for osteoporosis. The secondary aim of this study was to demonstrate the high prevalence of osteoporosis in patients with metaphyseal fractures.

results76.9% of our fracture patients had decreased bone density and 43.6% showed manifest osteoporosis in DXA (densitometry) measurements. Our questionnaire, identifying anamnestic risk factors, correlated highly significantly (p = 0.01) with reduced BMD, whereas seven bone-specific laboratory values (p = 0.046) correlated significantly.

conclusionsAnamnestic risk factors correlate with pathological BMD. The medical questionnaire used in this study would therefore function as a cost-effective primary diagnostic instrument for identification of osteoporosis patients.

Indexed as

Surveys and QuestionnairesAbsorptiometry, PhotonAdultAgedAged, 80 and overBone DensityComorbidityCost-Benefit AnalysisFamily HealthFemaleGermanyHumansMaleMass ScreeningMemory DisordersMenopause, Premature

Identifiers

PMID21849030
PMCPMC3176487
OpenAlexW2019579784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.